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Transcriptional protein SWT1 (SWT1)

Homo sapiens — UniProt Q5T5J6

Gene: SWT1Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Transcriptional protein SWT1 (SWT1) is a protein from Homo sapiens identified by UniProt accession Q5T5J6, 900 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.

  • UniProt accession: Q5T5J6; gene symbol SWT1.
  • Organism: Homo sapiens.
  • Length: 900 amino acids.
  • Top disease associations (Open Targets): cigarettes per day measurement, lymphocyte count and platelet crit.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameTranscriptional protein SWT1
UniProt accessionQ5T5J6
GeneSWT1
OrganismHomo sapiens
Length900 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (31)

Diseases linked to this target (Open Targets).

  • cigarettes per day measurement · score 0.28
  • lymphocyte count · score 0.28
  • platelet crit · score 0.22
  • neurodegenerative disease · score 0.22
  • gait measurement · score 0.21
  • grip strength measurement · score 0.21
  • sex hormone-binding globulin measurement · score 0.20
  • basophil count · score 0.20
  • monocyte count · score 0.17
  • leukocyte count · score 0.17

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5T5J6-F1alphafoldPREDICTED60.68—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T5J6.

Amino-acid sequence (900 residues)

MSSKESCGKK ETSQRKDTTT SSPNFGEKDK KERKTPASST SSSSIRSVSS EKRKLKSDHT DVLYYNIKRR QGLKRLSVEI DTLRRRPKIG SSSQRPIKLK EASYSNDNQI ILQSPSSNGT KKDIHKCVDF KPKDIKLTNA GSKLDHGIKS LSSPKIASDV KPKAEGQASE NKWSHLLVQR EKMKELKKGR NSKFRDNSEK CVLEKWKRNQ FSQDYNSNKI IKEPLGSRRQ KISFKIPIKS RDTLQKLVEE NVFNIDSNNS KTKQEEREYL ESSQVSLNVT RQKTEHLLSD FTYKRTVHEW KRKHHYDHQE SNDSHSRENL TQSFEAPCCS VSSESIQDAD QEMQIVEELH AARVGKSVDL PGELMSMEID LEDDVHSSSA NNTSDRKLLI VIDTNILMNH LKFVRILKTT EVPGFDKLVL IIPWVVMQEL DRMKEGKLLK RAQHKAIPAV HFINDSLKNQ DRKLWGQSIQ LASQKHYGLS DENNDDRVLK CCLQHQELFP CSFVILCTDD RNLRNKGLIS GVKSLSKEEL SAELLHLSLN TDVCHQPCIP KQQLKAETTP LKESYKEEST NSGLSILLES IVSDLEKSLG TGLSSILETE MKIAFGNLWM EILYLKPPWT LLHLLQCFKK HWLAVFGLVM EKNLLLTIES LYKNLRKANK AVDFTTVKFL LQDSRSLLHA FSTRSNYDGI LPQTFAQVNN LLQTFAEVKT KLKPNSSENT VTKKQEGTSL KNSHNQEITV FSSSHLPQPS RHQEIWSILE SVWITIYQNS TDVFQRLGSN SALTTSNIAS FEEAFICLQK LMAAVRDILE GIQRILAPNS NYQDVETLYN FLIKYEVNKN VKFTAQEIYD CVSQTEYREK LTIGCRQLVE MEYTMQQCNA SVYMEAKNRG WCEDMLNYRI

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SWT1?

The strongest Open Targets associations for SWT1 are cigarettes per day measurement, lymphocyte count, platelet crit, neurodegenerative disease and gait measurement.

How long is the SWT1 protein?

The Homo sapiens SWT1 protein (UniProt Q5T5J6) is 900 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5T5J6
GeneSWT1
OrganismHomo sapiens
Length900
Binders0
Diseases31
View on UniProt