Cyclin-J (CCNJ)
Homo sapiens — UniProt Q5T5M9
Data last refreshed: (UniProt release unknown)
Key facts
Cyclin-J (CCNJ) is a protein from Homo sapiens identified by UniProt accession Q5T5M9, 372 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.
- UniProt accession: Q5T5M9; gene symbol CCNJ.
- Organism: Homo sapiens.
- Length: 372 amino acids.
- Top disease associations (Open Targets): body height, sex hormone-binding globulin measurement and age at menopause.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cyclin-J |
|---|---|
| UniProt accession | Q5T5M9 |
| Gene | CCNJ |
| Organism | Homo sapiens |
| Length | 372 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (35)
Diseases linked to this target (Open Targets).
- body height · score 0.45
- sex hormone-binding globulin measurement · score 0.44
- age at menopause · score 0.43
- neurodegenerative disease · score 0.36
- BMI-adjusted waist circumference · score 0.36
- apolipoprotein B measurement · score 0.33
- mean corpuscular volume · score 0.29
- age at first sexual intercourse measurement · score 0.23
- antisocial behaviour measurement · score 0.15
- attention deficit hyperactivity disorder · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T5M9-F1 | alphafold | PREDICTED | 72.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T5M9.
Amino-acid sequence (372 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCNJ?
The strongest Open Targets associations for CCNJ are body height, sex hormone-binding globulin measurement, age at menopause, neurodegenerative disease and BMI-adjusted waist circumference.
How long is the CCNJ protein?
The Homo sapiens CCNJ protein (UniProt Q5T5M9) is 372 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T5M9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T5M9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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