Uncharacterized protein C6orf118 (C6orf118)
Homo sapiens — UniProt Q5T5N4
Data last refreshed: (UniProt release unknown)
Key facts
Uncharacterized protein C6orf118 (C6orf118) is a protein from Homo sapiens identified by UniProt accession Q5T5N4, 469 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.
- UniProt accession: Q5T5N4; gene symbol C6orf118.
- Organism: Homo sapiens.
- Length: 469 amino acids.
- Top disease associations (Open Targets): physical activity measurement, platelet count and PHF-tau measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Uncharacterized protein C6orf118 |
|---|---|
| UniProt accession | Q5T5N4 |
| Gene | C6orf118 |
| Organism | Homo sapiens |
| Length | 469 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (63)
Diseases linked to this target (Open Targets).
- physical activity measurement · score 0.29
- platelet count · score 0.22
- PHF-tau measurement · score 0.21
- insulin like growth factor measurement · score 0.19
- wheezing · score 0.14
- IGF-1 measurement · score 0.13
- body height · score 0.08
- azoospermia · score 0.08
- male infertility with teratozoospermia due to single gene mutation · score 0.07
- spermatogenic failure 3 · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T5N4-F1 | alphafold | PREDICTED | 70.43 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T5N4.
Amino-acid sequence (469 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C6orf118?
The strongest Open Targets associations for C6orf118 are physical activity measurement, platelet count, PHF-tau measurement, insulin like growth factor measurement and wheezing.
How long is the C6orf118 protein?
The Homo sapiens C6orf118 protein (UniProt Q5T5N4) is 469 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T5N4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T5N4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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