BEN domain-containing protein 3 (BEND3)
Homo sapiens — UniProt Q5T5X7
Data last refreshed: (UniProt release unknown)
Key facts
BEN domain-containing protein 3 (BEND3) is a protein from Homo sapiens identified by UniProt accession Q5T5X7, 828 residues long. MolForge cross-references it against 0 known binders and 86 disease associations.
- UniProt accession: Q5T5X7; gene symbol BEND3.
- Organism: Homo sapiens.
- Length: 828 amino acids.
- Top disease associations (Open Targets): eosinophil count, monocyte count and lymphocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | BEN domain-containing protein 3 |
|---|---|
| UniProt accession | Q5T5X7 |
| Gene | BEND3 |
| Organism | Homo sapiens |
| Length | 828 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (86)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.51
- monocyte count · score 0.47
- lymphocyte count · score 0.46
- mean corpuscular volume · score 0.43
- eosinophil percentage of leukocytes · score 0.43
- monocyte percentage of leukocytes · score 0.43
- type 2 diabetes mellitus · score 0.42
- serum albumin measurement · score 0.42
- lymphocyte percentage of leukocytes · score 0.41
- cortical thickness · score 0.40
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T5X7-F1 | alphafold | PREDICTED | 64.07 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T5X7.
Amino-acid sequence (828 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BEND3?
The strongest Open Targets associations for BEND3 are eosinophil count, monocyte count, lymphocyte count, mean corpuscular volume and eosinophil percentage of leukocytes.
How long is the BEND3 protein?
The Homo sapiens BEND3 protein (UniProt Q5T5X7) is 828 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T5X7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T5X7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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