Calmodulin-regulated spectrin-associated protein 1 (CAMSAP1)

Homo sapiens — UniProt Q5T5Y3

Gene: CAMSAP1Homo sapiensSwissProt reviewed

Data last refreshed: 2026-04-18 (UniProt release unknown)

Key facts

Calmodulin-regulated spectrin-associated protein 1 (CAMSAP1) is a protein from Homo sapiens identified by UniProt accession Q5T5Y3, 1602 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.

UniProt accession: Q5T5Y3; gene symbol CAMSAP1.
Organism: Homo sapiens.
Length: 1602 amino acids.
Top disease associations (Open Targets): neurodegenerative disease, genetic disorder and grip strength measurement.
3D structure: AlphaFold model available.

Target properties

Protein name	Calmodulin-regulated spectrin-associated protein 1
UniProt accession	Q5T5Y3
Gene	CAMSAP1
Organism	Homo sapiens
Length	1602 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (53)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.51
genetic disorder · score 0.19
grip strength measurement · score 0.16
cancer · score 0.05
hypoparathyroidism, familial isolated, 2 · score 0.05
neoplasm · score 0.04
pseudohypoparathyroidism type 2 · score 0.04
isolated focal cortical dysplasia · score 0.04
lissencephaly type 1 due to doublecortin gene mutation · score 0.03
small cell lung carcinoma · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5T5Y3-F1	alphafold	PREDICTED	54.33	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T5Y3.

Amino-acid sequence (1602 residues)

MVDASGRAAA EGWRKMEAPP DGAADLVPLD RYDAARAKIA ANLQWICAKA YGRDNIPEDL RDPFYVDQYE QEHIKPPVIK LLLSSELYCR VCSLILKGDQ VAALQGHQSV IQALSRKGIY VMESDDTPVT ESDLSRAPIK MSAHMAMVDA LMMAYTVEMI SIEKVVASVK RFSTFSASKE LPYDLEDAMV FWINKVNLKM REITEKEVKL KQQLLESPAH QKVRYRREHL SARQSPYFPL LEDLMRDGSD GAALLAVIHY YCPEQMKLDD ICLKEVTSMA DSLYNIRLLR EFSNEYLNKC FYLTLEDMLY APLVLKPNVM VFIAELFWWF ENVKPDFVQP RDVQELKDAK TVLHQKSSRP PVPISNATKR SFLGSPAAGT LAELQPPVQL PAEGCHRHYL HPEEPEYLGK GTAAFSPSHP LLPLRQKQQK SIQGEDIPDQ RHRSNSLTRV DGQPRGAAIA WPEKKTRPAS QPTPFALHHA ASCEVDPSSG DSISLARSIS KDSLASNIVN LTPQNQPHPT ATKSHGKSLL SNVSIEDEEE ELVAIVRADV VPQQADPEFP RASPRALGLT ANARSPQGQL DTSESKPDSF FLEPLMPAVL KPAKEKQVIT KEDERGEGRP RSIVSRRPSE GPQPLVRRKM TGSRDLNRTF TPIPCSEFPM GIDPTETGPL SVETAGEVCG GPLALGGFDP FPQGPSTDGF FLHVGRADED TEGRLYVSCS KSPNSHDSEP WTLLRQDSDS DVVDIEEAEH DFMGEAHPVV FSRYIGEEES AKLQEDMKVK EHEDKDDASG RSSPCLSTAS QMSSVSMASG SVKMTSFAER KLQRLNSCET KSSTSSSQKT TPDASESCPA PLTTWRQKRE QSPSQHGKDP ASLLASELVQ LHMQLEEKRR AIEAQKKKME ALSARQRLKL GKAAFLHVVK KGKAEAAPPL RPEHFAKEYS QHNGEDCGDA VSKTEDFLVK EEQREELLHE PQDVDKESLA FAQQHKAKDP VALHELERNK VISAALLEDT VGEVVDVNEC DLSIEKLNET ISTLQQAILK ISQQQEQLLM KSPTVPVPGS KNNSQDHKVK APVHFVEPLS PTGVAGHRKA PRLGQGRNSR SGRPAELKVP KDRPQGSSRS KTPTPSVETL PHLRPFPASS HPRTPTDPGL DSALEPSGDP HGKCLFDSYR LHDESNQRTL TLSSSKDANI LSEQMSLKEV LDASVKEVGS SSSDVSGKES VPVEEPLRSR ASLIEVDLSD LKAPDEDGEL VSLDGSADLV SEGDQKPGVG FFFKDEQKAE DELAKKRAAF LLKQQRKAEE ARVRKQQLEA EVELKRDEAR RKAEEDRVRK EEEKARRELI KQEYLRRKQQ QILEEQGLGK PKSKPKKPRP KSVHREESCS DSGTKCSSTP DNLSRTQSGS SLSLASAATT EPESVHSGGT PSQRVESMEA LPILSRNPSR STDRDWETAS AASSLASVAE YTGPKLFKEP SSKSNKPIIH NAISHCCLAG KVNEPHKNSI LEELEKCDAN HYIILFRDAG CQFRALYCYY PDTEEIYKLT GTGPKNITKK MIDKLYKYSS DRKQFNLIPA KTMSVSVDAL TIHNHLWQPK RPAVPKKAQT RK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CAMSAP1?

The strongest Open Targets associations for CAMSAP1 are neurodegenerative disease, genetic disorder, grip strength measurement, cancer and hypoparathyroidism, familial isolated, 2.

How long is the CAMSAP1 protein?

The Homo sapiens CAMSAP1 protein (UniProt Q5T5Y3) is 1602 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

UniProtKB Q5T5Y3 — name, gene, function, sequence, keywords (CC BY 4.0)
AlphaFold DB Q5T5Y3 — predicted 3D structure (CC BY 4.0)
Open Targets Platform — disease associations and tractability (CC0)

How this page is built: methodology · editorial policy & corrections.

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