Zinc finger protein 648 (ZNF648)
Homo sapiens — UniProt Q5T619
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 648 (ZNF648) is a protein from Homo sapiens identified by UniProt accession Q5T619, 568 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q5T619; gene symbol ZNF648.
- Organism: Homo sapiens.
- Length: 568 amino acids.
- Top disease associations (Open Targets): high density lipoprotein cholesterol measurement, lymphocyte count and leukocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 648 |
|---|---|
| UniProt accession | Q5T619 |
| Gene | ZNF648 |
| Organism | Homo sapiens |
| Length | 568 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- high density lipoprotein cholesterol measurement · score 0.39
- lymphocyte count · score 0.34
- leukocyte count · score 0.34
- apolipoprotein A 1 measurement · score 0.32
- myeloid white cell count · score 0.30
- apolipoprotein B measurement · score 0.30
- alcohol consumption measurement · score 0.29
- alcohol drinking · score 0.29
- total blood protein measurement · score 0.29
- mathematical ability · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T619-F1 | alphafold | PREDICTED | 59.92 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T619.
Amino-acid sequence (568 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF648?
The strongest Open Targets associations for ZNF648 are high density lipoprotein cholesterol measurement, lymphocyte count, leukocyte count, apolipoprotein A 1 measurement and myeloid white cell count.
How long is the ZNF648 protein?
The Homo sapiens ZNF648 protein (UniProt Q5T619) is 568 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T619 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T619 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.