Ataxin-7-like protein 2 (ATXN7L2)
Homo sapiens — UniProt Q5T6C5
Data last refreshed: (UniProt release unknown)
Key facts
Ataxin-7-like protein 2 (ATXN7L2) is a protein from Homo sapiens identified by UniProt accession Q5T6C5, 722 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q5T6C5; gene symbol ATXN7L2.
- Organism: Homo sapiens.
- Length: 722 amino acids.
- Top disease associations (Open Targets): chronotype measurement, self reported educational attainment and sortilin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ataxin-7-like protein 2 |
|---|---|
| UniProt accession | Q5T6C5 |
| Gene | ATXN7L2 |
| Organism | Homo sapiens |
| Length | 722 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- chronotype measurement · score 0.20
- self reported educational attainment · score 0.12
- sortilin measurement · score 0.11
- cognitive function measurement · score 0.09
- intelligence · score 0.08
- body mass index · score 0.08
- glomerular filtration rate · score 0.06
- tobacco smoke exposure measurement · score 0.05
- PR interval · score 0.05
- health study participation · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T6C5-F1 | alphafold | PREDICTED | 53.58 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T6C5.
Amino-acid sequence (722 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ATXN7L2?
The strongest Open Targets associations for ATXN7L2 are chronotype measurement, self reported educational attainment, sortilin measurement, cognitive function measurement and intelligence.
How long is the ATXN7L2 protein?
The Homo sapiens ATXN7L2 protein (UniProt Q5T6C5) is 722 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T6C5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T6C5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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