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Ubiquitin-associated protein 2 (UBAP2)

Homo sapiens — UniProt Q5T6F2

Gene: UBAP2Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Ubiquitin-associated protein 2 (UBAP2) is a protein from Homo sapiens identified by UniProt accession Q5T6F2, 1119 residues long. MolForge cross-references it against 0 known binders and 74 disease associations.

  • UniProt accession: Q5T6F2; gene symbol UBAP2.
  • Organism: Homo sapiens.
  • Length: 1119 amino acids.
  • Top disease associations (Open Targets): reticulocyte count, lymphocyte count and IGF-1 measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameUbiquitin-associated protein 2
UniProt accessionQ5T6F2
GeneUBAP2
OrganismHomo sapiens
Length1119 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (74)

Diseases linked to this target (Open Targets).

  • reticulocyte count · score 0.33
  • lymphocyte count · score 0.27
  • IGF-1 measurement · score 0.25
  • prostate carcinoma · score 0.23
  • type 2 diabetes mellitus · score 0.21
  • heel bone mineral density · score 0.21
  • reticulocyte measurement · score 0.18
  • hematocrit · score 0.18
  • Red cell distribution width · score 0.18
  • mean corpuscular hemoglobin concentration · score 0.16

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5T6F2-F1alphafoldPREDICTED43.16—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T6F2.

Amino-acid sequence (1119 residues)

MMTSVSSDHC RGAREKPQIS AAQSTQPQKQ VVQATAEQMR LAQVIFDKND SDFEAKVKQL MEVTGKNQDE CIVALHDCNG DVNKAINILL EGNSDTTSWE TVGCKKKNFA KENSENKENR EKKSEKESSR GRGNNNRKGR GGNRGREFRG EENGIDCNQV DKPSDRGKRA RGRGFGRGRG RGAGRFSTQG MGTFNPADYS DSTSTDVCGT KLVVWEAAQN GADEGTELAS NTHNIAQDLS NKSSYGLKGA WKNSVEEWTT EDWTEDLSET KVFTASSAPA ENHILPGQSI DLVALLQKPV PHSQASEANS FETSQQQGFG QALVFTNSQH NNQMAPGTGS STAVNSCSPQ SLSSVLGSGF GELAPPKMAN ITSSQILDQL KAPSLGQFTT TPSTQQNSTS HPTTTTSWDL KPPTSQSSVL SHLDFKSQPE PSPVLSQLSQ RQQHQSQAVT VPPPGLESFP SQAKLRESTP GDSPSTVNKL LQLPSTTIEN ISVSVHQPQP KHIKLAKRRI PPASKIPASA VEMPGSADVT GLNVQFGALE FGSEPSLSEF GSAPSSENSN QIPISLYSKS LSEPLNTSLS MTSAVQNSTY TTSVITSCSL TSSSLNSASP VAMSSSYDQS SVHNRIPYQS PVSSSESAPG TIMNGHGGGR SQQTLDTPKT TGPPSALPSV SSLPSTTSCT ALLPSTSQHT GDLTSSPLSQ LSSSLSSHQS SLSAHAALSS STSHTHASVE SASSHQSSAT FSTAATSVSS SASSGASLSS SMNTANSLCL GGTPASASSS SSRAAPLVTS GKAPPNLPQG VPPLLHNQYL VGPGGLLPAY PIYGYDELQM LQSRLPVDYY GIPFAAPTAL ASRDGSLANN PYPGDVTKFG RGDSASPAPA TTPAQPQQSQ SQTHHTAQQP FVNPALPPGY SYTGLPYYTG MPSAFQYGPT MFVPPASAKQ HGVNLSTPTP PFQQASGYGQ HGYSTGYDDL TQGTAAGDYS KGGYAGSSQA PNKSAGSGPG KGVSVSSSTT GLPDMTGSVY NKTQTFDKQG FHAGTPPPFS LPSVLGSTGP LASGAAPGYA PPPFLHILPA HQQPHSQLLH HHLPQDAQSG SGQRSQPSSL QPKSQASKPA YGNSPYWTN

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with UBAP2?

The strongest Open Targets associations for UBAP2 are reticulocyte count, lymphocyte count, IGF-1 measurement, prostate carcinoma and type 2 diabetes mellitus.

How long is the UBAP2 protein?

The Homo sapiens UBAP2 protein (UniProt Q5T6F2) is 1119 amino acids long.

Browse: Targets: U · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5T6F2
GeneUBAP2
OrganismHomo sapiens
Length1119
Binders0
Diseases74
View on UniProt