Probable gluconokinase (IDNK)
Homo sapiens — UniProt Q5T6J7
Data last refreshed: (UniProt release unknown)
Key facts
Probable gluconokinase (IDNK) is a protein from Homo sapiens identified by UniProt accession Q5T6J7, 187 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.
- UniProt accession: Q5T6J7; gene symbol IDNK.
- Organism: Homo sapiens.
- Length: 187 amino acids.
- Top disease associations (Open Targets): age at first sexual intercourse measurement, IGF-1 measurement and apolipoprotein A 1 measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Probable gluconokinase |
|---|---|
| UniProt accession | Q5T6J7 |
| Gene | IDNK |
| Organism | Homo sapiens |
| Length | 187 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (28)
Diseases linked to this target (Open Targets).
- age at first sexual intercourse measurement · score 0.17
- IGF-1 measurement · score 0.10
- apolipoprotein A 1 measurement · score 0.09
- bilirubin measurement · score 0.08
- hepatocellular carcinoma · score 0.05
- DNA methylation · score 0.04
- Abnormality of refraction · score 0.04
- contractures-ectodermal dysplasia-cleft lip/palate syndrome · score 0.03
- Sepsis · score 0.03
- body height · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T6J7-F1 | alphafold | PREDICTED | 88.54 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T6J7.
Amino-acid sequence (187 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IDNK?
The strongest Open Targets associations for IDNK are age at first sexual intercourse measurement, IGF-1 measurement, apolipoprotein A 1 measurement, bilirubin measurement and hepatocellular carcinoma.
How long is the IDNK protein?
The Homo sapiens IDNK protein (UniProt Q5T6J7) is 187 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T6J7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T6J7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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