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PHD finger protein 19 (PHF19)

Homo sapiens — UniProt Q5T6S3

Gene: PHF19Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

PHD finger protein 19 (PHF19) is a protein from Homo sapiens identified by UniProt accession Q5T6S3, 580 residues long. MolForge cross-references it against 0 known binders and 126 disease associations.

  • UniProt accession: Q5T6S3; gene symbol PHF19.
  • Organism: Homo sapiens.
  • Length: 580 amino acids.
  • Top disease associations (Open Targets): birth weight, lymphocyte count and leukocyte count.
  • 3D structure: AlphaFold model available.

Target properties

Protein namePHD finger protein 19
UniProt accessionQ5T6S3
GenePHF19
OrganismHomo sapiens
Length580 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (126)

Diseases linked to this target (Open Targets).

  • birth weight · score 0.43
  • lymphocyte count · score 0.27
  • leukocyte count · score 0.25
  • lean body mass · score 0.22
  • body height · score 0.19
  • high density lipoprotein cholesterol measurement · score 0.19
  • pulse pressure measurement · score 0.18
  • alkaline phosphatase measurement · score 0.18
  • anthropometric measurement · score 0.15
  • body weights and measures · score 0.15

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5T6S3-F1alphafoldPREDICTED69.06—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T6S3.

Amino-acid sequence (580 residues)

MENRALDPGT RDSYGATSHL PNKGALAKVK NNFKDLMSKL TEGQYVLCRW TDGLYYLGKI KRVSSSKQSC LVTFEDNSKY WVLWKDIQHA GVPGEEPKCN ICLGKTSGPL NEILICGKCG LGYHQQCHIP IAGSADQPLL TPWFCRRCIF ALAVRKGGAL KKGAIARTLQ AVKMVLSYQP EELEWDSPHR TNQQQCYCYC GGPGEWYLRM LQCYRCRQWF HEACTQCLNE PMMFGDRFYL FFCSVCNQGP EYIERLPLRW VDVVHLALYN LGVQSKKKYF DFEEILAFVN HHWELLQLGK LTSTPVTDRG PHLLNALNSY KSRFLCGKEI KKKKCIFRLR IRVPPNPPGK LLPDKGLLPN ENSASSELRK RGKSKPGLLP HEFQQQKRRV YRRKRSKFLL EDAIPSSDFT SAWSTNHHLA SIFDFTLDEI QSLKSASSGQ TFFSDVDSTD AASTSGSAST SLSYDSRWTV GSRKRKLAAK AYMPLRAKRW AAELDGRCPS DSSAEGASVP ERPDEGIDSH TFESISEDDS SLSHLKSSIT NYFGAAGRLA CGEKYQVLAR RVTPEGKVQY LVEWEGTTPY

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with PHF19?

The strongest Open Targets associations for PHF19 are birth weight, lymphocyte count, leukocyte count, lean body mass and body height.

How long is the PHF19 protein?

The Homo sapiens PHF19 protein (UniProt Q5T6S3) is 580 amino acids long.

Browse: Targets: P · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5T6S3
GenePHF19
OrganismHomo sapiens
Length580
Binders0
Diseases126
View on UniProt