Queuosine 5'-phosphate N-glycosylase/hydrolase (QNG1)
Homo sapiens — UniProt Q5T6V5
Data last refreshed: (UniProt release unknown)
Key facts
Queuosine 5'-phosphate N-glycosylase/hydrolase (QNG1) is a protein from Homo sapiens identified by UniProt accession Q5T6V5, 341 residues long. MolForge cross-references it against 0 known binders and 73 disease associations.
- UniProt accession: Q5T6V5; gene symbol QNG1.
- Organism: Homo sapiens.
- Length: 341 amino acids.
- Top disease associations (Open Targets): IGF-1 measurement, HbA1c measurement and smoking initiation.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Queuosine 5'-phosphate N-glycosylase/hydrolase |
|---|---|
| UniProt accession | Q5T6V5 |
| Gene | QNG1 |
| Organism | Homo sapiens |
| Length | 341 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (73)
Diseases linked to this target (Open Targets).
- IGF-1 measurement · score 0.35
- HbA1c measurement · score 0.30
- smoking initiation · score 0.25
- leukocyte count · score 0.24
- neutrophil count · score 0.23
- smoking behavior · score 0.23
- age at menarche · score 0.22
- triglyceride measurement · score 0.21
- smoking status measurement · score 0.21
- body fat distribution · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T6V5-F1 | alphafold | PREDICTED | 96.22 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T6V5.
Amino-acid sequence (341 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with QNG1?
The strongest Open Targets associations for QNG1 are IGF-1 measurement, HbA1c measurement, smoking initiation, leukocyte count and neutrophil count.
How long is the QNG1 protein?
The Homo sapiens QNG1 protein (UniProt Q5T6V5) is 341 amino acids long.
Browse: Targets: Q · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T6V5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T6V5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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