Protein KPLCE (KPLCE)

About Protein KPLCE

Protein KPLCE (KPLCE) is a protein from Homo sapiens identified by UniProt accession Q5T750, 250 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.

Target properties

Protein name	Protein KPLCE
UniProt accession	Q5T750
Gene	KPLCE
Organism	Homo sapiens
Length	250 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (14)

Diseases linked to this target (Open Targets).

psoriasis · score 0.20
atopic eczema · score 0.02
rosacea · score 0.01
squamous cell lung carcinoma · score 0.01
gastric carcinoma · score 0.01
skin disease · score 0.00
cutaneous lupus erythematosus · score 0.00
Pneumonia · score 0.00
periodontal disorder · score 0.00
popliteal pterygium syndrome · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5T750-F1	alphafold	PREDICTED	44.93	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T750.

Amino-acid sequence (250 residues)

MCDQQKQPQF PPSCVKGSGL GAGQGSNGAS VKCPVPCQTQ TVCVTGPAPC PTQTYVKYQV PCQTQTYVKC PAPCQRTYVK YPTPCQTYVK CPAPCQTTYV KCPTPCQTYV KCPAPCQMTY IKSPAPCQTQ TCYVQGASPC QSYYVQAPAS GSTSQYCVTD PCSAPCSTSY CCLAPRTFGV SPLRRWIQRP QNCNTGSSGC CENSGSSGCC GSGGCGCSCG CGSSGCCCLG IIPMRSRGPA CCDHEDDCCC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards