Late cornified envelope protein 1F (LCE1F)
Homo sapiens — UniProt Q5T754
Data last refreshed: (UniProt release unknown)
Key facts
Late cornified envelope protein 1F (LCE1F) is a protein from Homo sapiens identified by UniProt accession Q5T754, 118 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.
- UniProt accession: Q5T754; gene symbol LCE1F.
- Organism: Homo sapiens.
- Length: 118 amino acids.
- Top disease associations (Open Targets): glioblastoma multiforme, breast adenocarcinoma and prostate adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Late cornified envelope protein 1F |
|---|---|
| UniProt accession | Q5T754 |
| Gene | LCE1F |
| Organism | Homo sapiens |
| Length | 118 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (10)
Diseases linked to this target (Open Targets).
- glioblastoma multiforme · score 0.23
- breast adenocarcinoma · score 0.22
- prostate adenocarcinoma · score 0.21
- head and neck squamous cell carcinoma · score 0.18
- urinary bladder cancer · score 0.11
- melorheostosis · score 0.04
- cancer · score 0.01
- hematocrit · score 0.00
- triple-negative breast cancer · score 0.00
- gonorrhea · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T754-F1 | alphafold | PREDICTED | 51.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T754.
Amino-acid sequence (118 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LCE1F?
The strongest Open Targets associations for LCE1F are glioblastoma multiforme, breast adenocarcinoma, prostate adenocarcinoma, head and neck squamous cell carcinoma and urinary bladder cancer.
How long is the LCE1F protein?
The Homo sapiens LCE1F protein (UniProt Q5T754) is 118 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T754 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T754 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.