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Kinesin-like protein KIF24 (KIF24)

Homo sapiens — UniProt Q5T7B8

Gene: KIF24Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Kinesin-like protein KIF24 (KIF24) is a protein from Homo sapiens identified by UniProt accession Q5T7B8, 1368 residues long. MolForge cross-references it against 0 known binders and 48 disease associations.

  • UniProt accession: Q5T7B8; gene symbol KIF24.
  • Organism: Homo sapiens.
  • Length: 1368 amino acids.
  • Top disease associations (Open Targets): diet measurement, skeletal dysplasia and Skeletal dysplasia.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameKinesin-like protein KIF24
UniProt accessionQ5T7B8
GeneKIF24
OrganismHomo sapiens
Length1368 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (48)

Diseases linked to this target (Open Targets).

  • diet measurement · score 0.38
  • skeletal dysplasia · score 0.37
  • Skeletal dysplasia · score 0.37
  • asphyxiating thoracic dystrophy 3 · score 0.33
  • short rib-polydactyly syndrome, Majewski type · score 0.33
  • Short rib-polydactyly syndrome, Verma-Naumoff type · score 0.33
  • Red cell distribution width · score 0.25
  • neurodegenerative disease · score 0.21
  • mean arterial pressure · score 0.13
  • reticulocyte measurement · score 0.12

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5T7B8-F1alphafoldPREDICTED51.42—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T7B8.

Amino-acid sequence (1368 residues)

MASWLYECLC EAELAQYYSH FTALGLQKID ELAKITMKDY SKLGVHDMND RKRLFQLIKI IKIMQEEDKA VSIPERHLQT SSLRIKSQEL RSGPRRQLNF DSPADNKDRN ASNDGFEMCS LSDFSANEQK STYLKVLEHM LPDDSQYHTK TGILNATAGD SYVQTEISTS LFSPNYLSAI LGDCDIPIIQ RISHVSGYNY GIPHSCIRQN TSEKQNPWTE MEKIRVCVRK RPLGMREVRR GEINIITVED KETLLVHEKK EAVDLTQYIL QHVFYFDEVF GEACTNQDVY MKTTHPLIQH IFNGGNATCF AYGQTGAGKT YTMIGTHENP GLYALAAKDI FRQLEVSQPR KHLFVWISFY EIYCGQLYDL LNRRKRLFAR EDSKHMVQIV GLQELQVDSV ELLLEVILKG SKERSTGATG VNADSSRSHA VIQIQIKDSA KRTFGRISFI DLAGSERAAD ARDSDRQTKM EGAEINQSLL ALKECIRALD QEHTHTPFRQ SKLTQVLKDS FIGNAKTCMI ANISPSHVAT EHTLNTLRYA DRVKELKKGI KCCTSVTSRN RTSGNSSPKR IQSSPGALSE DKCSPKKVKL GFQQSLTVAA PGSTRGKVHP LTSHPPNIPF TSAPKVSGKR GGSRGSPSQE WVIHASPVKG TVRSGHVAKK KPEESAPLCS EKNRMGNKTV LGWESRASGP GEGLVRGKLS TKCKKVQTVQ PVQKQLVSRV ELSFGNAHHR AEYSQDSQRG TPARPASEAW TNIPPHQKER EEHLRFYHQQ FQQPPLLQQK LKYQPLKRSL RQYRPPEGQL TNETPPLFHS YSENHDGAQV EELDDSDFSE DSFSHISSQR ATKQRNTLEN SEDSFFLHQT WGQGPEKQVA ERQQSLFSSP RTGDKKDLTK SWVDSRDPIN HRRAALDHSC SPSKGPVDWS RENSTSSGPS PRDSLAEKPY CSQVDFIYRQ ERGGGSSFDL RKDASQSEVS GENEGNLPSP EEDGFTISLS HVAVPGSPDQ RDTVTTPLRE VSADGPIQVT STVKNGHAVP GEDPRGQLGT HAEYASGLMS PLTMSLLENP DNEGSPPSEQ LVQDGATHSL VAESTGGPVV SHTVPSGDQE AALPVSSATR HLWLSSSPPD NKPGGDLPAL SPSPIRQHPA DKLPSREADL GEACQSRETV LFSHEHMGSE QYDADAEETG LDGSWGFPGK PFTTIHMGVP HSGPTLTPRT GSSDVADQLW AQERKHPTRL GWQEFGLSTD PIKLPCNSEN VTWLKPRPIS RCLARPSSPL VPSCSPKTAG TLRQPTLEQA QQVVIRAHQE QLDEMAELGF KEETLMSQLA SNDFEDFVTQ LDEIMVLKSK CIQSLRSQLQ LYLTCHGPTA APEGTVPS

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with KIF24?

The strongest Open Targets associations for KIF24 are diet measurement, skeletal dysplasia, Skeletal dysplasia, asphyxiating thoracic dystrophy 3 and short rib-polydactyly syndrome, Majewski type.

How long is the KIF24 protein?

The Homo sapiens KIF24 protein (UniProt Q5T7B8) is 1368 amino acids long.

Browse: Targets: K · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5T7B8
GeneKIF24
OrganismHomo sapiens
Length1368
Binders0
Diseases48
View on UniProt