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Adipolin (C1QTNF12)

Homo sapiens — UniProt Q5T7M4

Gene: C1QTNF12Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Adipolin (C1QTNF12) is a protein from Homo sapiens identified by UniProt accession Q5T7M4, 302 residues long. MolForge cross-references it against 0 known binders and 68 disease associations.

  • UniProt accession: Q5T7M4; gene symbol C1QTNF12.
  • Organism: Homo sapiens.
  • Length: 302 amino acids.
  • Top disease associations (Open Targets): hair color, hypothyroidism and hair colour measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameAdipolin
UniProt accessionQ5T7M4
GeneC1QTNF12
OrganismHomo sapiens
Length302 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (68)

Diseases linked to this target (Open Targets).

  • hair color · score 0.24
  • hypothyroidism · score 0.23
  • hair colour measurement · score 0.21
  • systemic lupus erythematosus · score 0.20
  • thyroid disease · score 0.19
  • Thyroid preparation use measurement · score 0.09
  • Crohn's disease · score 0.08
  • ankylosing spondylitis · score 0.08
  • sclerosing cholangitis · score 0.08
  • ulcerative colitis · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5T7M4-F1alphafoldPREDICTED73.70—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T7M4.

Amino-acid sequence (302 residues)

MRRWAWAAVV VLLGPQLVLL GGVGARREAQ RTQQPGQRAD PPNATASASS REGLPEAPKP SQASGPEFSD AHMTWLNFVR RPDDGALRKR CGSRDKKPRD LFGPPGPPGA EVTAETLLHE FQELLKEATE RRFSGLLDPL LPQGAGLRLV GEAFHCRLQG PRRVDKRTLV ELHGFQAPAA QGAFLRGSGL SLASGRFTAP VSGIFQFSAS LHVDHSELQG KARLRARDVV CVLICIESLC QRHTCLEAVS GLESNSRVFT LQVQGLLQLQ AGQYASVFVD NGSGAVLTIQ AGSSFSGLLL GT

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with C1QTNF12?

The strongest Open Targets associations for C1QTNF12 are hair color, hypothyroidism, hair colour measurement, systemic lupus erythematosus and thyroid disease.

How long is the C1QTNF12 protein?

The Homo sapiens C1QTNF12 protein (UniProt Q5T7M4) is 302 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5T7M4
GeneC1QTNF12
OrganismHomo sapiens
Length302
Binders0
Diseases68
View on UniProt