Divergent protein kinase domain 1A (DIPK1A)
Homo sapiens — UniProt Q5T7M9
Data last refreshed: (UniProt release unknown)
Key facts
Divergent protein kinase domain 1A (DIPK1A) is a protein from Homo sapiens identified by UniProt accession Q5T7M9, 428 residues long. MolForge cross-references it against 0 known binders and 78 disease associations.
- UniProt accession: Q5T7M9; gene symbol DIPK1A.
- Organism: Homo sapiens.
- Length: 428 amino acids.
- Top disease associations (Open Targets): Blackfan-Diamond anemia, Diamond-Blackfan anemia and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Divergent protein kinase domain 1A |
|---|---|
| UniProt accession | Q5T7M9 |
| Gene | DIPK1A |
| Organism | Homo sapiens |
| Length | 428 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (78)
Diseases linked to this target (Open Targets).
- Blackfan-Diamond anemia · score 0.57
- Diamond-Blackfan anemia · score 0.57
- platelet count · score 0.43
- genetic disorder · score 0.41
- lean body mass · score 0.35
- platelet crit · score 0.35
- FEV/FVC ratio · score 0.34
- hemangioma · score 0.34
- atrial heart septal defect · score 0.34
- pulmonary arterial hypertension · score 0.34
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T7M9-F1 | alphafold | PREDICTED | 83.45 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T7M9.
Amino-acid sequence (428 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DIPK1A?
The strongest Open Targets associations for DIPK1A are Blackfan-Diamond anemia, Diamond-Blackfan anemia, platelet count, genetic disorder and lean body mass.
How long is the DIPK1A protein?
The Homo sapiens DIPK1A protein (UniProt Q5T7M9) is 428 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T7M9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T7M9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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