LINE-1 type transposase domain-containing protein 1 (L1TD1)
Homo sapiens — UniProt Q5T7N2
Data last refreshed: (UniProt release unknown)
Key facts
LINE-1 type transposase domain-containing protein 1 (L1TD1) is a protein from Homo sapiens identified by UniProt accession Q5T7N2, 865 residues long. MolForge cross-references it against 0 known binders and 57 disease associations.
- UniProt accession: Q5T7N2; gene symbol L1TD1.
- Organism: Homo sapiens.
- Length: 865 amino acids.
- Top disease associations (Open Targets): colorectal cancer, neuroblastoma and lean body mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | LINE-1 type transposase domain-containing protein 1 |
|---|---|
| UniProt accession | Q5T7N2 |
| Gene | L1TD1 |
| Organism | Homo sapiens |
| Length | 865 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (57)
Diseases linked to this target (Open Targets).
- colorectal cancer · score 0.31
- neuroblastoma · score 0.30
- lean body mass · score 0.17
- body mass index · score 0.16
- body fat percentage · score 0.16
- body height · score 0.15
- smoking behavior · score 0.13
- serum alanine aminotransferase measurement · score 0.13
- fat body mass · score 0.13
- chronotype measurement · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T7N2-F1 | alphafold | PREDICTED | 55.53 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T7N2.
Amino-acid sequence (865 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with L1TD1?
The strongest Open Targets associations for L1TD1 are colorectal cancer, neuroblastoma, lean body mass, body mass index and body fat percentage.
How long is the L1TD1 protein?
The Homo sapiens L1TD1 protein (UniProt Q5T7N2) is 865 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T7N2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T7N2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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