Late cornified envelope protein 1B (LCE1B)
Homo sapiens — UniProt Q5T7P3
Data last refreshed: (UniProt release unknown)
Key facts
Late cornified envelope protein 1B (LCE1B) is a protein from Homo sapiens identified by UniProt accession Q5T7P3, 118 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q5T7P3; gene symbol LCE1B.
- Organism: Homo sapiens.
- Length: 118 amino acids.
- Top disease associations (Open Targets): breast adenocarcinoma, neurodegenerative disease and clear cell renal carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Late cornified envelope protein 1B |
|---|---|
| UniProt accession | Q5T7P3 |
| Gene | LCE1B |
| Organism | Homo sapiens |
| Length | 118 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.22
- neurodegenerative disease · score 0.21
- clear cell renal carcinoma · score 0.18
- esophageal cancer · score 0.17
- blood protein measurement · score 0.11
- squamous cell lung carcinoma · score 0.11
- endometrial cancer · score 0.10
- melorheostosis · score 0.04
- metabolite measurement · score 0.03
- atopic eczema · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T7P3-F1 | alphafold | PREDICTED | 51.24 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T7P3.
Amino-acid sequence (118 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LCE1B?
The strongest Open Targets associations for LCE1B are breast adenocarcinoma, neurodegenerative disease, clear cell renal carcinoma, esophageal cancer and blood protein measurement.
How long is the LCE1B protein?
The Homo sapiens LCE1B protein (UniProt Q5T7P3) is 118 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T7P3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T7P3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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