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Uncharacterized protein C1orf185 (C1orf185)

Homo sapiens — UniProt Q5T7R7

Gene: C1orf185Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Uncharacterized protein C1orf185 (C1orf185) is a protein from Homo sapiens identified by UniProt accession Q5T7R7, 199 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.

  • UniProt accession: Q5T7R7; gene symbol C1orf185.
  • Organism: Homo sapiens.
  • Length: 199 amino acids.
  • Top disease associations (Open Targets): calcium measurement, diastolic blood pressure and brain volume measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameUncharacterized protein C1orf185
UniProt accessionQ5T7R7
GeneC1orf185
OrganismHomo sapiens
Length199 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (30)

Diseases linked to this target (Open Targets).

  • calcium measurement · score 0.29
  • diastolic blood pressure · score 0.28
  • brain volume measurement · score 0.28
  • erythrocyte count · score 0.21
  • cerebellar volume measurement · score 0.19
  • QRS duration · score 0.17
  • mean corpuscular volume · score 0.14
  • multiple myeloma · score 0.13
  • atrial fibrillation · score 0.13
  • body height · score 0.12

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5T7R7-F1alphafoldPREDICTED62.58—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T7R7.

Amino-acid sequence (199 residues)

MASPKGFFNY LTYFLAAGAV TLGIGFFALA SALWFLICKR REIFQNSKFK AIDERCRQRP SMAKIKSHSQ CVFISRNFHT GRFQLQEEQR KKEAAHIKAI KDHSKDEPQL ATKNIICDPS ETSSTTNRSS VTLSLSTLPS DSYYSQSIEA ADDWFSDDSL VKRNSPMPSL GEPLMEKVFS YLSTISLEEG TESVLNDTL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with C1orf185?

The strongest Open Targets associations for C1orf185 are calcium measurement, diastolic blood pressure, brain volume measurement, erythrocyte count and cerebellar volume measurement.

How long is the C1orf185 protein?

The Homo sapiens C1orf185 protein (UniProt Q5T7R7) is 199 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5T7R7
GeneC1orf185
OrganismHomo sapiens
Length199
Binders0
Diseases30
View on UniProt