RAB6-interacting golgin (GORAB)
Homo sapiens — UniProt Q5T7V8
Data last refreshed: (UniProt release unknown)
Key facts
RAB6-interacting golgin (GORAB) is a protein from Homo sapiens identified by UniProt accession Q5T7V8, 369 residues long. MolForge cross-references it against 0 known binders and 51 disease associations.
- UniProt accession: Q5T7V8; gene symbol GORAB.
- Organism: Homo sapiens.
- Length: 369 amino acids.
- Top disease associations (Open Targets): geroderma osteodysplastica, genetic disorder and heel bone mineral density.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RAB6-interacting golgin |
|---|---|
| UniProt accession | Q5T7V8 |
| Gene | GORAB |
| Organism | Homo sapiens |
| Length | 369 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (51)
Diseases linked to this target (Open Targets).
- geroderma osteodysplastica · score 0.78
- genetic disorder · score 0.41
- heel bone mineral density · score 0.37
- Skeletal dysplasia · score 0.37
- BMI-adjusted waist-hip ratio · score 0.34
- blood protein measurement · score 0.27
- androgenetic alopecia · score 0.27
- atrial fibrillation · score 0.26
- skin pigmentation · score 0.25
- atrial flutter · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T7V8-F1 | alphafold | PREDICTED | 70.92 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T7V8.
Amino-acid sequence (369 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GORAB?
The strongest Open Targets associations for GORAB are geroderma osteodysplastica, genetic disorder, heel bone mineral density, Skeletal dysplasia and BMI-adjusted waist-hip ratio.
How long is the GORAB protein?
The Homo sapiens GORAB protein (UniProt Q5T7V8) is 369 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T7V8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T7V8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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