Zinc finger protein 618 (ZNF618)
Homo sapiens — UniProt Q5T7W0
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 618 (ZNF618) is a protein from Homo sapiens identified by UniProt accession Q5T7W0, 954 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.
- UniProt accession: Q5T7W0; gene symbol ZNF618.
- Organism: Homo sapiens.
- Length: 954 amino acids.
- Top disease associations (Open Targets): systolic blood pressure, pulse pressure measurement and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 618 |
|---|---|
| UniProt accession | Q5T7W0 |
| Gene | ZNF618 |
| Organism | Homo sapiens |
| Length | 954 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (36)
Diseases linked to this target (Open Targets).
- systolic blood pressure · score 0.41
- pulse pressure measurement · score 0.38
- neurodegenerative disease · score 0.37
- body mass index · score 0.34
- serum metabolite measurement · score 0.34
- bone density · score 0.31
- urate measurement · score 0.31
- arterial stiffness measurement · score 0.30
- chronotype measurement · score 0.29
- self reported educational attainment · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T7W0-F1 | alphafold | PREDICTED | 64.34 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T7W0.
Amino-acid sequence (954 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF618?
The strongest Open Targets associations for ZNF618 are systolic blood pressure, pulse pressure measurement, neurodegenerative disease, body mass index and serum metabolite measurement.
How long is the ZNF618 protein?
The Homo sapiens ZNF618 protein (UniProt Q5T7W0) is 954 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T7W0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T7W0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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