Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 (TSTD2)
Homo sapiens — UniProt Q5T7W7
Data last refreshed: (UniProt release unknown)
Key facts
Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 (TSTD2) is a protein from Homo sapiens identified by UniProt accession Q5T7W7, 516 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q5T7W7; gene symbol TSTD2.
- Organism: Homo sapiens.
- Length: 516 amino acids.
- Top disease associations (Open Targets): sex hormone-binding globulin measurement, metabolite measurement and chronic kidney disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 |
|---|---|
| UniProt accession | Q5T7W7 |
| Gene | TSTD2 |
| Organism | Homo sapiens |
| Length | 516 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- sex hormone-binding globulin measurement · score 0.06
- metabolite measurement · score 0.04
- chronic kidney disease · score 0.04
- FEV/FVC ratio · score 0.03
- atherosclerosis · score 0.03
- Stroke · score 0.01
- neoplasm · score 0.01
- cancer · score 0.01
- Sepsis · score 0.01
- cerebral infarction · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T7W7-F1 | alphafold | PREDICTED | 80.70 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T7W7.
Amino-acid sequence (516 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TSTD2?
The strongest Open Targets associations for TSTD2 are sex hormone-binding globulin measurement, metabolite measurement, chronic kidney disease, FEV/FVC ratio and atherosclerosis.
How long is the TSTD2 protein?
The Homo sapiens TSTD2 protein (UniProt Q5T7W7) is 516 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T7W7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T7W7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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