Late cornified envelope-like proline-rich protein 1 (LELP1)
Homo sapiens — UniProt Q5T871
Data last refreshed: (UniProt release unknown)
Key facts
Late cornified envelope-like proline-rich protein 1 (LELP1) is a protein from Homo sapiens identified by UniProt accession Q5T871, 98 residues long. MolForge cross-references it against 0 known binders and 86 disease associations.
- UniProt accession: Q5T871; gene symbol LELP1.
- Organism: Homo sapiens.
- Length: 98 amino acids.
- Top disease associations (Open Targets): glioblastoma multiforme, breast adenocarcinoma and prostate adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Late cornified envelope-like proline-rich protein 1 |
|---|---|
| UniProt accession | Q5T871 |
| Gene | LELP1 |
| Organism | Homo sapiens |
| Length | 98 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (86)
Diseases linked to this target (Open Targets).
- glioblastoma multiforme · score 0.23
- breast adenocarcinoma · score 0.22
- prostate adenocarcinoma · score 0.21
- pancreatic adenocarcinoma · score 0.18
- neuroblastoma · score 0.13
- squamous cell lung carcinoma · score 0.11
- Blackfan-Diamond anemia · score 0.08
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome · score 0.06
- alpha-thalassemia-myelodysplastic syndrome · score 0.06
- hemoglobin D disease · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T871-F1 | alphafold | PREDICTED | 67.80 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T871.
Amino-acid sequence (98 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LELP1?
The strongest Open Targets associations for LELP1 are glioblastoma multiforme, breast adenocarcinoma, prostate adenocarcinoma, pancreatic adenocarcinoma and neuroblastoma.
How long is the LELP1 protein?
The Homo sapiens LELP1 protein (UniProt Q5T871) is 98 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T871 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T871 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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