Protein phosphatase 1 regulatory subunit 26 (PPP1R26)
Homo sapiens — UniProt Q5T8A7
Data last refreshed: (UniProt release unknown)
Key facts
Protein phosphatase 1 regulatory subunit 26 (PPP1R26) is a protein from Homo sapiens identified by UniProt accession Q5T8A7, 1209 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.
- UniProt accession: Q5T8A7; gene symbol PPP1R26.
- Organism: Homo sapiens.
- Length: 1209 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, chemotherapy-induced cytotoxicity measurement and Ovarian Endometriosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein phosphatase 1 regulatory subunit 26 |
|---|---|
| UniProt accession | Q5T8A7 |
| Gene | PPP1R26 |
| Organism | Homo sapiens |
| Length | 1209 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (27)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.35
- chemotherapy-induced cytotoxicity measurement · score 0.28
- Ovarian Endometriosis · score 0.23
- neuroinflammatory disorder · score 0.21
- sphingolipid measurement · score 0.14
- hepatocellular carcinoma · score 0.07
- attention deficit hyperactivity disorder · score 0.06
- Tourette syndrome · score 0.05
- schizophrenia 15 · score 0.05
- attention deficit-hyperactivity disorder 8 · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T8A7-F1 | alphafold | PREDICTED | 46.51 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T8A7.
Amino-acid sequence (1209 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PPP1R26?
The strongest Open Targets associations for PPP1R26 are neurodegenerative disease, chemotherapy-induced cytotoxicity measurement, Ovarian Endometriosis, neuroinflammatory disorder and sphingolipid measurement.
How long is the PPP1R26 protein?
The Homo sapiens PPP1R26 protein (UniProt Q5T8A7) is 1209 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T8A7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T8A7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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