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RNA-binding protein 26 (RBM26)

Homo sapiens — UniProt Q5T8P6

Gene: RBM26Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

RNA-binding protein 26 (RBM26) is a protein from Homo sapiens identified by UniProt accession Q5T8P6, 1007 residues long. MolForge cross-references it against 0 known binders and 52 disease associations.

  • UniProt accession: Q5T8P6; gene symbol RBM26.
  • Organism: Homo sapiens.
  • Length: 1007 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, age at menopause and adolescent idiopathic scoliosis.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameRNA-binding protein 26
UniProt accessionQ5T8P6
GeneRBM26
OrganismHomo sapiens
Length1007 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (52)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.49
  • age at menopause · score 0.24
  • adolescent idiopathic scoliosis · score 0.24
  • platelet component distribution width · score 0.23
  • systolic blood pressure · score 0.23
  • body mass index · score 0.13
  • body fat percentage · score 0.12
  • lean body mass · score 0.11
  • fat body mass · score 0.11
  • body weight · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5T8P6-F1alphafoldPREDICTED57.88—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T8P6.

Amino-acid sequence (1007 residues)

MVSKMIIENF EALKSWLSKT LEPICDADPS ALAKYVLALV KKDKSEKELK ALCIDQLDVF LQKETQIFVE KLFDAVNTKS YLPPPEQPSS GSLKVEFFPH QEKDIKKEEI TKEEEREKKF SRRLNHSPPQ SSSRYRENRS RDERKKDDRS RKRDYDRNPP RRDSYRDRYN RRRGRSRSYS RSRSRSWSKE RLRERDRDRS RTRSRSRTRS RERDLVKPKY DLDRTDPLEN NYTPVSSVPS ISSGHYPVPT LSSTITVIAP THHGNNTTES WSEFHEDQVD HNSYVRPPMP KKRCRDYDEK GFCMRGDMCP FDHGSDPVVV EDVNLPGMLP FPAQPPVVEG PPPPGLPPPP PILTPPPVNL RPPVPPPGPL PPSLPPVTGP PPPLPPLQPS GMDAPPNSAT SSVPTVVTTG IHHQPPPAPP SLFTADTYDT DGYNPEAPSI TNTSRPMYRH RVHAQRPNLI GLTSGDMDLP PREKPPNKSS MRIVVDSESR KRTIGSGEPG VPTKKTWFDK PNFNRTNSPG FQKKVQFGNE NTKLELRKVP PELNNISKLN EHFSRFGTLV NLQVAYNGDP EGALIQFATY EEAKKAISST EAVLNNRFIK VYWHREGSTQ QLQTTSPKVM QPLVQQPILP VVKQSVKERL GPVPSSTIEP AEAQSASSDL PQNVTKLSVK DRLGFVSKPS VSATEKVLST STGLTKTVYN PAALKAAQKT LLVSTSAVDN NEAQKKKQEA LKLQQDVRKR KQEILEKHIE TQKMLISKLE KNKTMKSEDK AEIMKTLEVL TKNITKLKDE VKAASPGRCL PKSIKTKTQM QKELLDTELD LYKKMQAGEE VTELRRKYTE LQLEAAKRGI LSSGRGRGIH SRGRGAVHGR GRGRGRGRGV PGHAVVDHRP RALEISAFTE SDREDLLPHF AQYGEIEDCQ IDDSSLHAVI TFKTRAEAEA AAVHGARFKG QDLKLAWNKP VTNISAVETE EVEPDEEEFQ EESLVDDSLL QDDDEEEEDN ESRSWRR

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with RBM26?

The strongest Open Targets associations for RBM26 are neurodegenerative disease, age at menopause, adolescent idiopathic scoliosis, platelet component distribution width and systolic blood pressure.

How long is the RBM26 protein?

The Homo sapiens RBM26 protein (UniProt Q5T8P6) is 1007 amino acids long.

Browse: Targets: R · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5T8P6
GeneRBM26
OrganismHomo sapiens
Length1007
Binders0
Diseases52
View on UniProt