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Sodium/hydrogen exchanger 11 (SLC9C2)

Homo sapiens — UniProt Q5TAH2

Gene: SLC9C2Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Sodium/hydrogen exchanger 11 (SLC9C2) is a protein from Homo sapiens identified by UniProt accession Q5TAH2, 1124 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.

  • UniProt accession: Q5TAH2; gene symbol SLC9C2.
  • Organism: Homo sapiens.
  • Length: 1124 amino acids.
  • Top disease associations (Open Targets): adolescent idiopathic scoliosis, glioblastoma multiforme and breast adenocarcinoma.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameSodium/hydrogen exchanger 11
UniProt accessionQ5TAH2
GeneSLC9C2
OrganismHomo sapiens
Length1124 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (21)

Diseases linked to this target (Open Targets).

  • adolescent idiopathic scoliosis · score 0.27
  • glioblastoma multiforme · score 0.18
  • breast adenocarcinoma · score 0.16
  • blood protein measurement · score 0.13
  • head and neck squamous cell carcinoma · score 0.12
  • body mass index · score 0.10
  • intelligence · score 0.09
  • schizophrenia · score 0.06
  • rheumatoid arthritis · score 0.06
  • systemic lupus erythematosus · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5TAH2-F1alphafoldPREDICTED77.87—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5TAH2.

Amino-acid sequence (1124 residues)

MSSYFWAQNE SNRPDLLCGQ PADYLVEEKH FTTLVCFIVV LGGLLKMCLK NCEVIVLTIL SLSGFVIGHM AYNSVEVHQI VYPLLRTSSF SLYSYFSPLI IFMVALDVEF YTLKKMFWQV LLTGLISFST ASIIIGYVVI KFNKDSWDLQ SCLLFSITLG IIDPLRSVNS LKTIGISKIY IDLIRGESLI ICSIASIFFG NFRGNRIHFS IFRDLHVGIE LSYDILGSII FGYWCAKIIQ CILADVFSNM LTNIILCFSM VYMTFYIVEF LGMSGTLALA AVGLNLDSLT FKPKIELVIT KFLRIFSSVY EHLIYAFFGI VIGCGELSHY EFHTIPFIFI LFTTVNLVRL LTILLVSPIL MHSNYEYNWR WGVVITWSGI KGVFNLLWAP DVYNLAERKV EVPQMFILYV QVISLLTMGI NSYVMTQSAR KLDLCVLSLP RQMILQNATQ HIQEIVQNTI TLFKTEKILT NVNWTLVEDK TRIEYIPFSH VSHNDMKTES TTDEALMEEA RLHVAAIQMS SFEKQRNNGI LEIEAARILI GAAKCYYSIQ GKFMSIYDVS TYMRTRSWLI KFKNVLTFLE YCIEKIHFIP PESNTFLTFI FHIVFSEEFE YTGQIINLIY IYPMIIHLWP MARGLNVSAL ISINYYFMFL YVLESTLKII ILKRKYFQQC WNTLEFFILV IGIIDIFCVY FVKLRPDNLA LIQLTVIMGY LRIIRFLPLF KIIVPILIRI ADVQIKKRLS LMYSITKGYI KSQEDAKLLI KQIAVCESIY QKLCEILETN KQDAVKELVL MEHEGRDVVI ALKTKQAIRN VIAKALKNLT FLCSRGIIDK HEVIEINKVL LKKLKALNNF PKAIPPPTPD IYLHNIIWLE GKDVLIDFFK ERAKLACFDS GDTICKGGEM PQGIYLIISG MAILHSLSPT FGIESNQRCD RGSRDMFTEF CTTGDIIGEL SCLLKREIEY TVICETSLQA CFISLEDLYE GFDAFWPSLE YKIWLKLALS TAYQYFESSL IDEDLRFQNC VMFNQAYVET LSSYSDMIID NMTMKFVIIV YGSVIDTKTE EPYFAPCIIP TTCEQVQGTS DLSKLLIIQA SELTQRNSNT NVMASVNTVF EQPGKNINGR QKMS

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SLC9C2?

The strongest Open Targets associations for SLC9C2 are adolescent idiopathic scoliosis, glioblastoma multiforme, breast adenocarcinoma, blood protein measurement and head and neck squamous cell carcinoma.

How long is the SLC9C2 protein?

The Homo sapiens SLC9C2 protein (UniProt Q5TAH2) is 1124 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5TAH2
GeneSLC9C2
OrganismHomo sapiens
Length1124
Binders0
Diseases21
View on UniProt