Uncharacterized protein C9orf153 (C9orf153)
Homo sapiens — UniProt Q5TBE3
Data last refreshed: (UniProt release unknown)
Key facts
Uncharacterized protein C9orf153 (C9orf153) is a protein from Homo sapiens identified by UniProt accession Q5TBE3, 101 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.
- UniProt accession: Q5TBE3; gene symbol C9orf153.
- Organism: Homo sapiens.
- Length: 101 amino acids.
- Top disease associations (Open Targets): Red cell distribution width, mathematical ability and cortical surface area measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Uncharacterized protein C9orf153 |
|---|---|
| UniProt accession | Q5TBE3 |
| Gene | C9orf153 |
| Organism | Homo sapiens |
| Length | 101 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (37)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.19
- mathematical ability · score 0.18
- cortical surface area measurement · score 0.18
- FEV/FVC ratio · score 0.16
- lean body mass · score 0.15
- cortical thickness · score 0.15
- reticulocyte measurement · score 0.14
- BMI-adjusted hip circumference · score 0.14
- appendicular lean mass · score 0.13
- reticulocyte count · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5TBE3-F1 | alphafold | PREDICTED | 65.15 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5TBE3.
Amino-acid sequence (101 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C9orf153?
The strongest Open Targets associations for C9orf153 are Red cell distribution width, mathematical ability, cortical surface area measurement, FEV/FVC ratio and lean body mass.
How long is the C9orf153 protein?
The Homo sapiens C9orf153 protein (UniProt Q5TBE3) is 101 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5TBE3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5TBE3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.