Radial spoke head protein 4 homolog A (RSPH4A)
Homo sapiens — UniProt Q5TD94
Data last refreshed: (UniProt release unknown)
Key facts
Radial spoke head protein 4 homolog A (RSPH4A) is a protein from Homo sapiens identified by UniProt accession Q5TD94, 716 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.
- UniProt accession: Q5TD94; gene symbol RSPH4A.
- Organism: Homo sapiens.
- Length: 716 amino acids.
- Top disease associations (Open Targets): primary ciliary dyskinesia, bronchiectasis and Bronchiectasis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Radial spoke head protein 4 homolog A |
|---|---|
| UniProt accession | Q5TD94 |
| Gene | RSPH4A |
| Organism | Homo sapiens |
| Length | 716 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (38)
Diseases linked to this target (Open Targets).
- primary ciliary dyskinesia · score 0.75
- bronchiectasis · score 0.37
- Bronchiectasis · score 0.37
- Recurrent respiratory infections · score 0.37
- sinusitis · score 0.37
- rhinitis · score 0.37
- Nasal congestion · score 0.37
- otitis media with effusion · score 0.37
- Otitis media · score 0.37
- deafness · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5TD94-F1 | alphafold | PREDICTED | 67.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5TD94.
Amino-acid sequence (716 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RSPH4A?
The strongest Open Targets associations for RSPH4A are primary ciliary dyskinesia, bronchiectasis, Bronchiectasis, Recurrent respiratory infections and sinusitis.
How long is the RSPH4A protein?
The Homo sapiens RSPH4A protein (UniProt Q5TD94) is 716 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5TD94 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5TD94 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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