Protein DDI1 homolog 2 (DDI2)
Homo sapiens — UniProt Q5TDH0
Data last refreshed: (UniProt release unknown)
Key facts
Protein DDI1 homolog 2 (DDI2) is a protein from Homo sapiens identified by UniProt accession Q5TDH0, 399 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.
- UniProt accession: Q5TDH0; gene symbol DDI2.
- Organism: Homo sapiens.
- Length: 399 amino acids.
- Top disease associations (Open Targets): chronotype measurement, systolic blood pressure and pulse pressure measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein DDI1 homolog 2 |
|---|---|
| UniProt accession | Q5TDH0 |
| Gene | DDI2 |
| Organism | Homo sapiens |
| Length | 399 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (28)
Diseases linked to this target (Open Targets).
- chronotype measurement · score 0.30
- systolic blood pressure · score 0.25
- pulse pressure measurement · score 0.21
- metabolite measurement · score 0.16
- type 2 diabetes mellitus · score 0.11
- brain measurement · score 0.10
- heel bone mineral density · score 0.08
- high density lipoprotein cholesterol measurement · score 0.07
- serum urea measurement · score 0.06
- Miyoshi myopathy · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5TDH0-F1 | alphafold | PREDICTED | 79.55 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5TDH0.
Amino-acid sequence (399 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DDI2?
The strongest Open Targets associations for DDI2 are chronotype measurement, systolic blood pressure, pulse pressure measurement, metabolite measurement and type 2 diabetes mellitus.
How long is the DDI2 protein?
The Homo sapiens DDI2 protein (UniProt Q5TDH0) is 399 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5TDH0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5TDH0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.