About Dynein axonemal assembly factor 9
Dynein axonemal assembly factor 9 (DNAAF9) is a protein
from Homo sapiens identified by UniProt accession
Q5TEA3, 1177 residues long.
MolForge cross-references it against 0 known binders and
22 disease associations.
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
Disease associations (22)
Diseases linked to this target (Open Targets).
- hemoglobin measurement · score 0.33
- neurofibrillary tangles measurement · score 0.25
- body height · score 0.25
- chronic hepatitis C virus infection · score 0.24
- appendicular lean mass · score 0.24
- cortical thickness · score 0.22
- insulin like growth factor measurement · score 0.22
- hematocrit · score 0.18
- reticulocyte count · score 0.18
- sitting height measurement · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
Experimental structures are not indexed in MolForge yet —
search RCSB PDB for Q5TEA3.
Amino-acid sequence (1177 residues)
MDVYPPRRQG LPRARSPGGS SRGSPSVSCS RLRQVQSILT QSSKSRPDGI LCILGIDSRY NEGCRELANY LLFGLYNQNT SDFEKTGFSE EVLDDVIILI KSDSVHLYCN PVNFRYLLPY VAHWRNLHFH CMTENEYEDE EAAEEFKITS FVDMVRDCSR IGIPYSSQGH LQIFDMFVVE KWPIVQAFAL EGIGGDGFFT MKYELQDVSL NLWNVYSKMD PMSLESLLSD DLVAFEHQWT SFFANFDTEI PFLLELSESQ AGEPFRSYFS HGMISSHITE NSPNRQPFVL FGNHSTRENL NAGNFNFPSE GHLVRSTGPG GSFAKHMVAQ CVSPKGPLAC SRTYFFGATH VPYLGGDSKL PKKTEQIRLL SQIYAAVIEA VLAGIACYAK TSSLTKAKEV AEQTLGSGLD SFELIPFKAA LRSKMTFHIH AVNNQGRIVP LDSEDSLSFV KTACMAVYDI PDLLGGNGCL GSVVFSESFL TSQILVKEKD GTVTTETSSV VLTAAVPRFC SWLVEDNEVK LSEKTQQAVR GDESFLGTYL TGGEGAYLYS SNLQSWPEEG NVHFFSSGLL FSHCRHRSII ISKDHMNSIS FYDGDSTSTV AALLIDFKSS LLPHLPVHFH GSSNFLMIAL FPKSKIYQAF YSEVFSLWKQ QDNSGISLKV IQEDGLSVEQ KRLHSSAQKL FSALSQPAGE KRSSLKLLSA KLPELDWFLQ HFAISSISQE PVMRTHLPVL LQQAEINTTH RIESDKVIIS IVTGLPGCHA SELCAFLVTL HKECGRWMVY RQIMDSSECF HAAHFQRYLS SALEAQQNRS ARQSAYIRKK TRLLVVLQGY TDVIDVVQAL QTHPDSNVKA SFTIGAITAC VEPMSCYMEH RFLFPKCLDQ CSQGLVSNVV FTSHTTEQRH PLLVQLQSLI RAANPAAAFI LAENGIVTRN EDIELILSEN SFSSPEMLRS RYLMYPGWYE GKLNAGSVYP LMVQICVWFG RPLEKTRFVA KCKAIQSSIK PSPFSGNIYH ILGKVKFSDS ERTMEVCYNT LANSLSIMPV LEGPTPPPDS KSVSQDSSGQ QECYLVFIGC SLKEDSIKDW LRQSAKQKPQ RKALKTRGML TQQEIRSIHV KRHLEPLPAG YFYNGTQFVN FFGDKTDFHP LMDQFMNDYV EEANREIEKY NQELEQQEYH DLFELKP
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