Protein sel-1 homolog 2 (SEL1L2)
Homo sapiens — UniProt Q5TEA6
Data last refreshed: (UniProt release unknown)
Key facts
Protein sel-1 homolog 2 (SEL1L2) is a protein from Homo sapiens identified by UniProt accession Q5TEA6, 688 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q5TEA6; gene symbol SEL1L2.
- Organism: Homo sapiens.
- Length: 688 amino acids.
- Top disease associations (Open Targets): bone density, urate measurement and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein sel-1 homolog 2 |
|---|---|
| UniProt accession | Q5TEA6 |
| Gene | SEL1L2 |
| Organism | Homo sapiens |
| Length | 688 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- bone density · score 0.32
- urate measurement · score 0.32
- neurodegenerative disease · score 0.19
- drug use measurement · score 0.09
- ovarian carcinoma · score 0.02
- bipolar disorder · score 0.02
- Neurodevelopmental delay · score 0.01
- breast ductal carcinoma in situ · score 0.00
- invasive breast ductal carcinoma · score 0.00
- partial epilepsy · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5TEA6-F1 | alphafold | PREDICTED | 85.24 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5TEA6.
Amino-acid sequence (688 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SEL1L2?
The strongest Open Targets associations for SEL1L2 are bone density, urate measurement, neurodegenerative disease, drug use measurement and ovarian carcinoma.
How long is the SEL1L2 protein?
The Homo sapiens SEL1L2 protein (UniProt Q5TEA6) is 688 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5TEA6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5TEA6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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