Protein THEMIS2 (THEMIS2)
Homo sapiens — UniProt Q5TEJ8
Data last refreshed: (UniProt release unknown)
Key facts
Protein THEMIS2 (THEMIS2) is a protein from Homo sapiens identified by UniProt accession Q5TEJ8, 643 residues long. MolForge cross-references it against 0 known binders and 64 disease associations.
- UniProt accession: Q5TEJ8; gene symbol THEMIS2.
- Organism: Homo sapiens.
- Length: 643 amino acids.
- Top disease associations (Open Targets): monocyte count, eosinophil count and Red cell distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein THEMIS2 |
|---|---|
| UniProt accession | Q5TEJ8 |
| Gene | THEMIS2 |
| Organism | Homo sapiens |
| Length | 643 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (64)
Diseases linked to this target (Open Targets).
- monocyte count · score 0.35
- eosinophil count · score 0.27
- Red cell distribution width · score 0.24
- HbA1c measurement · score 0.21
- leukocyte count · score 0.19
- neutrophil count · score 0.15
- platelet count · score 0.14
- myeloid white cell count · score 0.14
- lymphocyte count · score 0.14
- platelet component distribution width · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5TEJ8-F1 | alphafold | PREDICTED | 74.76 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5TEJ8.
Amino-acid sequence (643 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with THEMIS2?
The strongest Open Targets associations for THEMIS2 are monocyte count, eosinophil count, Red cell distribution width, HbA1c measurement and leukocyte count.
How long is the THEMIS2 protein?
The Homo sapiens THEMIS2 protein (UniProt Q5TEJ8) is 643 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5TEJ8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5TEJ8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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