Uncharacterized protein C6orf163 (C6orf163)

Homo sapiens — UniProt Q5TEZ5

Gene: C6orf163Homo sapiensSwissProt reviewed

About Uncharacterized protein C6orf163

Uncharacterized protein C6orf163 (C6orf163) is a protein from Homo sapiens identified by UniProt accession Q5TEZ5, 329 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.

Target properties

Protein nameUncharacterized protein C6orf163
UniProt accessionQ5TEZ5
GeneC6orf163
OrganismHomo sapiens
Length329 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (31)

Diseases linked to this target (Open Targets).

  • eosinophil count · score 0.26
  • neurodegenerative disease · score 0.25
  • IGF-1 measurement · score 0.16
  • monocyte percentage of leukocytes · score 0.11
  • leukocyte count · score 0.08
  • lymphocyte percentage of leukocytes · score 0.08
  • entorhinal cortical volume · score 0.07
  • Alzheimer disease · score 0.07
  • atrial fibrillation · score 0.07
  • eosinophil percentage of leukocytes · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5TEZ5-F1alphafoldPREDICTED83.70—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5TEZ5.

Amino-acid sequence (329 residues)

MIRNSDYKNF VCCAVCNKII PPAPFGKTFK RIHEYKPLKT RFYTHKDILD IGANILKKEE QFQEDILREH IAKAEAEVWA QANERQKQAV EKALEEANDR HKIEIQILKE EHQKDLQEVT AKTKTEMYQN MDDEMKREHL AAEQRMVHRI QRIMMECHRE KVEAVEKARA EERHIAQEAI QAQKSKAVEE IVNTGVTVIK DEKTSVARLM REKEHEMSIL YGIAQRQRQE EVQEVLQEAE KTHQATLGNM MDKLANTQGE LLSIAKQLGI MTNWKDFLEE ELQETRMAFQ KYINYTFPKL SPGHADFILP ERKKTPSNLV IKENKTTLD

Explore Uncharacterized protein C6orf163 with MolForge

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Quick facts

UniProtQ5TEZ5
GeneC6orf163
OrganismHomo sapiens
Length329
Binders0
Diseases31
View on UniProt