Zinc finger C2HC domain-containing protein 1B (ZC2HC1B)
Homo sapiens — UniProt Q5TFG8
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger C2HC domain-containing protein 1B (ZC2HC1B) is a protein from Homo sapiens identified by UniProt accession Q5TFG8, 222 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: Q5TFG8; gene symbol ZC2HC1B.
- Organism: Homo sapiens.
- Length: 222 amino acids.
- Top disease associations (Open Targets): erythrocyte count, eosinophil count and testosterone measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger C2HC domain-containing protein 1B |
|---|---|
| UniProt accession | Q5TFG8 |
| Gene | ZC2HC1B |
| Organism | Homo sapiens |
| Length | 222 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- erythrocyte count · score 0.31
- eosinophil count · score 0.12
- testosterone measurement · score 0.06
- sitting height measurement · score 0.03
- vital capacity · score 0.03
- body mass index · score 0.03
- adult onset asthma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5TFG8-F1 | alphafold | PREDICTED | 73.23 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5TFG8.
Amino-acid sequence (222 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZC2HC1B?
The strongest Open Targets associations for ZC2HC1B are erythrocyte count, eosinophil count, testosterone measurement, sitting height measurement and vital capacity.
How long is the ZC2HC1B protein?
The Homo sapiens ZC2HC1B protein (UniProt Q5TFG8) is 222 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5TFG8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5TFG8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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