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Failed axon connections homolog (FAXC)

Homo sapiens — UniProt Q5TGI0

Gene: FAXCHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Failed axon connections homolog (FAXC) is a protein from Homo sapiens identified by UniProt accession Q5TGI0, 409 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.

  • UniProt accession: Q5TGI0; gene symbol FAXC.
  • Organism: Homo sapiens.
  • Length: 409 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, testosterone measurement and body height.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameFailed axon connections homolog
UniProt accessionQ5TGI0
GeneFAXC
OrganismHomo sapiens
Length409 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (33)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.49
  • testosterone measurement · score 0.30
  • body height · score 0.20
  • serum alanine aminotransferase measurement · score 0.19
  • depressive symptom measurement · score 0.17
  • mathematical ability · score 0.14
  • insomnia measurement · score 0.14
  • prostate carcinoma · score 0.11
  • prostate cancer · score 0.11
  • Familial prostate cancer · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5TGI0-F1alphafoldPREDICTED74.58—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5TGI0.

Amino-acid sequence (409 residues)

MHWGVGFASS RPCVVDLSWN QSISFFGWWA GSEEPFSFYG DIIAFPLQDY GGIMAGLGSD PWWKKTLYLT GGALLAAAAY LLHELLVIRK QQEIDSKDAI ILHQFARPNN GVPSLSPFCL KMETYLRMAD LPYQNYFGGK LSAQGKMPWI EYNHEKVSGT EFIIDFLEEK LGVNLNKNLG PHERAISRAV TKMVEEHFYW TLAYCQWVDN LNETRKMLSL SGGGPFSNLL RWVVCHITKG IVKREMHGHG IGRFSEEEIY MLMEKDMRSL AGLLGDKKYI MGPKLSTLDA TVFGHLAQAM WTLPGTRPER LIKGELINLA MYCERIRRKF WPEWHHDDDN TIYESEESSE GSKTHTPLLD FSFYSRTETF EDEGAENSFS RTPDTDFTGH SLFDSDVDMD DYTDHEQCK

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with FAXC?

The strongest Open Targets associations for FAXC are neurodegenerative disease, testosterone measurement, body height, serum alanine aminotransferase measurement and depressive symptom measurement.

How long is the FAXC protein?

The Homo sapiens FAXC protein (UniProt Q5TGI0) is 409 amino acids long.

Browse: Targets: F · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5TGI0
GeneFAXC
OrganismHomo sapiens
Length409
Binders0
Diseases33
View on UniProt