Sterile alpha motif domain-containing protein 5 (SAMD5)
Homo sapiens — UniProt Q5TGI4
Data last refreshed: (UniProt release unknown)
Key facts
Sterile alpha motif domain-containing protein 5 (SAMD5) is a protein from Homo sapiens identified by UniProt accession Q5TGI4, 173 residues long. MolForge cross-references it against 0 known binders and 59 disease associations.
- UniProt accession: Q5TGI4; gene symbol SAMD5.
- Organism: Homo sapiens.
- Length: 173 amino acids.
- Top disease associations (Open Targets): chronotype measurement, body height and pathological myopia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sterile alpha motif domain-containing protein 5 |
|---|---|
| UniProt accession | Q5TGI4 |
| Gene | SAMD5 |
| Organism | Homo sapiens |
| Length | 173 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (59)
Diseases linked to this target (Open Targets).
- chronotype measurement · score 0.42
- body height · score 0.34
- pathological myopia · score 0.33
- feeling tense measurement · score 0.33
- unipolar depression · score 0.33
- insomnia measurement · score 0.33
- childhood trauma measurement · score 0.33
- protein measurement · score 0.33
- renal cell carcinoma · score 0.24
- subiculum volume · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5TGI4-F1 | alphafold | PREDICTED | 70.48 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5TGI4.
Amino-acid sequence (173 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SAMD5?
The strongest Open Targets associations for SAMD5 are chronotype measurement, body height, pathological myopia, feeling tense measurement and unipolar depression.
How long is the SAMD5 protein?
The Homo sapiens SAMD5 protein (UniProt Q5TGI4) is 173 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5TGI4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5TGI4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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