Maestro heat-like repeat-containing protein family member 9 (MROH9)
Homo sapiens — UniProt Q5TGP6
Data last refreshed: (UniProt release unknown)
Key facts
Maestro heat-like repeat-containing protein family member 9 (MROH9) is a protein from Homo sapiens identified by UniProt accession Q5TGP6, 573 residues long. MolForge cross-references it against 0 known binders and 82 disease associations.
- UniProt accession: Q5TGP6; gene symbol MROH9.
- Organism: Homo sapiens.
- Length: 573 amino acids.
- Top disease associations (Open Targets): BMI-adjusted hip circumference, BMI-adjusted waist circumference and vital capacity.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Maestro heat-like repeat-containing protein family member 9 |
|---|---|
| UniProt accession | Q5TGP6 |
| Gene | MROH9 |
| Organism | Homo sapiens |
| Length | 573 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (82)
Diseases linked to this target (Open Targets).
- BMI-adjusted hip circumference · score 0.36
- BMI-adjusted waist circumference · score 0.30
- vital capacity · score 0.28
- Abnormality of refraction · score 0.27
- forced expiratory volume · score 0.27
- skin aging measurement · score 0.26
- central corneal thickness · score 0.25
- grip strength measurement · score 0.24
- heel bone mineral density · score 0.18
- hair shape measurement · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5TGP6-F1 | alphafold | PREDICTED | 77.17 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5TGP6.
Amino-acid sequence (573 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MROH9?
The strongest Open Targets associations for MROH9 are BMI-adjusted hip circumference, BMI-adjusted waist circumference, vital capacity, Abnormality of refraction and forced expiratory volume.
How long is the MROH9 protein?
The Homo sapiens MROH9 protein (UniProt Q5TGP6) is 573 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5TGP6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5TGP6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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