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MICOS complex subunit MIC10 (MICOS10)

Homo sapiens — UniProt Q5TGZ0

Gene: MICOS10Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

MICOS complex subunit MIC10 (MICOS10) is a protein from Homo sapiens identified by UniProt accession Q5TGZ0, 78 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.

  • UniProt accession: Q5TGZ0; gene symbol MICOS10.
  • Organism: Homo sapiens.
  • Length: 78 amino acids.
  • Top disease associations (Open Targets): hypothyroidism, thyroid stimulating hormone measurement and hormone measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameMICOS complex subunit MIC10
UniProt accessionQ5TGZ0
GeneMICOS10
OrganismHomo sapiens
Length78 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (47)

Diseases linked to this target (Open Targets).

  • hypothyroidism · score 0.29
  • thyroid stimulating hormone measurement · score 0.28
  • hormone measurement · score 0.27
  • nontoxic goiter · score 0.27
  • sex hormone-binding globulin measurement · score 0.26
  • heel bone mineral density · score 0.25
  • Thyrotoxicosis · score 0.25
  • body height · score 0.24
  • Hashimoto's thyroiditis · score 0.22
  • myxedema · score 0.21

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5TGZ0-F1alphafoldPREDICTED73.27—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5TGZ0.

Amino-acid sequence (78 residues)

MSESELGRKW DRCLADAVVK IGTGFGLGIV FSLTFFKRRM WPLAFGSGMG LGMAYSNCQH DFQAPYLLHG KYVKEQEQ

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with MICOS10?

The strongest Open Targets associations for MICOS10 are hypothyroidism, thyroid stimulating hormone measurement, hormone measurement, nontoxic goiter and sex hormone-binding globulin measurement.

How long is the MICOS10 protein?

The Homo sapiens MICOS10 protein (UniProt Q5TGZ0) is 78 amino acids long.

Browse: Targets: M · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5TGZ0
GeneMICOS10
OrganismHomo sapiens
Length78
Binders0
Diseases47
View on UniProt