Meiosis inhibitor protein 1 (MEI1)
Homo sapiens — UniProt Q5TIA1
Data last refreshed: (UniProt release unknown)
Key facts
Meiosis inhibitor protein 1 (MEI1) is a protein from Homo sapiens identified by UniProt accession Q5TIA1, 1274 residues long. MolForge cross-references it against 0 known binders and 167 disease associations.
- UniProt accession: Q5TIA1; gene symbol MEI1.
- Organism: Homo sapiens.
- Length: 1274 amino acids.
- Top disease associations (Open Targets): Hydatidiform Mole, complete hydatidiform mole and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Meiosis inhibitor protein 1 |
|---|---|
| UniProt accession | Q5TIA1 |
| Gene | MEI1 |
| Organism | Homo sapiens |
| Length | 1274 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (167)
Diseases linked to this target (Open Targets).
- Hydatidiform Mole · score 0.57
- complete hydatidiform mole · score 0.37
- neurodegenerative disease · score 0.32
- body height · score 0.22
- lean body mass · score 0.18
- sitting height measurement · score 0.17
- fat body mass · score 0.15
- appendicular lean mass · score 0.15
- birth weight · score 0.15
- forced expiratory volume · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5TIA1-F1 | alphafold | PREDICTED | 83.67 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5TIA1.
Amino-acid sequence (1274 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MEI1?
The strongest Open Targets associations for MEI1 are Hydatidiform Mole, complete hydatidiform mole, neurodegenerative disease, body height and lean body mass.
How long is the MEI1 protein?
The Homo sapiens MEI1 protein (UniProt Q5TIA1) is 1274 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5TIA1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5TIA1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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