Coiled-coil domain-containing protein 181 (CCDC181)
Homo sapiens — UniProt Q5TID7
Data last refreshed: (UniProt release unknown)
Key facts
Coiled-coil domain-containing protein 181 (CCDC181) is a protein from Homo sapiens identified by UniProt accession Q5TID7, 509 residues long. MolForge cross-references it against 0 known binders and 67 disease associations.
- UniProt accession: Q5TID7; gene symbol CCDC181.
- Organism: Homo sapiens.
- Length: 509 amino acids.
- Top disease associations (Open Targets): venous thromboembolism, electrocardiography and blood coagulation disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coiled-coil domain-containing protein 181 |
|---|---|
| UniProt accession | Q5TID7 |
| Gene | CCDC181 |
| Organism | Homo sapiens |
| Length | 509 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (67)
Diseases linked to this target (Open Targets).
- venous thromboembolism · score 0.29
- electrocardiography · score 0.14
- blood coagulation disease · score 0.13
- QT interval · score 0.09
- Ovarian Endometriosis · score 0.09
- Menorrhagia · score 0.09
- age-related macular degeneration · score 0.08
- X-linked retinal dysplasia · score 0.08
- cor pulmonale · score 0.08
- breast cancer · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5TID7-F1 | alphafold | PREDICTED | 67.65 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5TID7.
Amino-acid sequence (509 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCDC181?
The strongest Open Targets associations for CCDC181 are venous thromboembolism, electrocardiography, blood coagulation disease, QT interval and Ovarian Endometriosis.
How long is the CCDC181 protein?
The Homo sapiens CCDC181 protein (UniProt Q5TID7) is 509 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5TID7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5TID7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.