Ankyrin repeat domain-containing protein 45 (ANKRD45)
Homo sapiens — UniProt Q5TZF3
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat domain-containing protein 45 (ANKRD45) is a protein from Homo sapiens identified by UniProt accession Q5TZF3, 266 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.
- UniProt accession: Q5TZF3; gene symbol ANKRD45.
- Organism: Homo sapiens.
- Length: 266 amino acids.
- Top disease associations (Open Targets): intelligence, body mass index and leukocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat domain-containing protein 45 |
|---|---|
| UniProt accession | Q5TZF3 |
| Gene | ANKRD45 |
| Organism | Homo sapiens |
| Length | 266 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (28)
Diseases linked to this target (Open Targets).
- intelligence · score 0.11
- body mass index · score 0.11
- leukocyte count · score 0.10
- attention deficit hyperactivity disorder · score 0.09
- attention deficit-hyperactivity disorder 8 · score 0.07
- schizophrenia 15 · score 0.07
- mathematical ability · score 0.06
- schizophrenia · score 0.06
- Tourette syndrome · score 0.06
- Phelan-McDermid syndrome · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5TZF3-F1 | alphafold | PREDICTED | 80.95 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5TZF3.
Amino-acid sequence (266 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANKRD45?
The strongest Open Targets associations for ANKRD45 are intelligence, body mass index, leukocyte count, attention deficit hyperactivity disorder and attention deficit-hyperactivity disorder 8.
How long is the ANKRD45 protein?
The Homo sapiens ANKRD45 protein (UniProt Q5TZF3) is 266 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5TZF3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5TZF3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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