Transmembrane protein 164 (TMEM164)
Homo sapiens — UniProt Q5U3C3
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 164 (TMEM164) is a protein from Homo sapiens identified by UniProt accession Q5U3C3, 297 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q5U3C3; gene symbol TMEM164.
- Organism: Homo sapiens.
- Length: 297 amino acids.
- Top disease associations (Open Targets): adolescent idiopathic scoliosis, neurodegenerative disease and lung carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 164 |
|---|---|
| UniProt accession | Q5U3C3 |
| Gene | TMEM164 |
| Organism | Homo sapiens |
| Length | 297 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- adolescent idiopathic scoliosis · score 0.14
- neurodegenerative disease · score 0.01
- lung carcinoma · score 0.01
- tuberculosis · score 0.01
- cancer · score 0.01
- lung adenocarcinoma · score 0.01
- hepatocellular carcinoma · score 0.01
- acne · score 0.01
- non-alcoholic steatohepatitis · score 0.00
- vulvar intraepithelial neoplasia · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5U3C3-F1 | alphafold | PREDICTED | 89.83 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5U3C3.
Amino-acid sequence (297 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM164?
The strongest Open Targets associations for TMEM164 are adolescent idiopathic scoliosis, neurodegenerative disease, lung carcinoma, tuberculosis and cancer.
How long is the TMEM164 protein?
The Homo sapiens TMEM164 protein (UniProt Q5U3C3) is 297 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5U3C3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5U3C3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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