RNA-binding E3 ubiquitin-protein ligase MEX3C (MEX3C)
Homo sapiens — UniProt Q5U5Q3
Data last refreshed: (UniProt release unknown)
Key facts
RNA-binding E3 ubiquitin-protein ligase MEX3C (MEX3C) is a protein from Homo sapiens identified by UniProt accession Q5U5Q3, 659 residues long. MolForge cross-references it against 0 known binders and 109 disease associations.
- UniProt accession: Q5U5Q3; gene symbol MEX3C.
- Organism: Homo sapiens.
- Length: 659 amino acids.
- Top disease associations (Open Targets): platelet count, self reported educational attainment and urate measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RNA-binding E3 ubiquitin-protein ligase MEX3C |
|---|---|
| UniProt accession | Q5U5Q3 |
| Gene | MEX3C |
| Organism | Homo sapiens |
| Length | 659 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (109)
Diseases linked to this target (Open Targets).
- platelet count · score 0.43
- self reported educational attainment · score 0.42
- urate measurement · score 0.39
- bone density · score 0.39
- hypertension · score 0.34
- platelet crit · score 0.32
- systolic blood pressure · score 0.31
- cardiovascular disease · score 0.30
- Agents acting on the renin-angiotensin system use measurement · score 0.30
- mathematical ability · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5U5Q3-F1 | alphafold | PREDICTED | 59.54 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5U5Q3.
Amino-acid sequence (659 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MEX3C?
The strongest Open Targets associations for MEX3C are platelet count, self reported educational attainment, urate measurement, bone density and hypertension.
How long is the MEX3C protein?
The Homo sapiens MEX3C protein (UniProt Q5U5Q3) is 659 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5U5Q3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5U5Q3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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