Complex III assembly factor LYRM7 (LYRM7)
Homo sapiens — UniProt Q5U5X0
Data last refreshed: (UniProt release unknown)
Key facts
Complex III assembly factor LYRM7 (LYRM7) is a protein from Homo sapiens identified by UniProt accession Q5U5X0, 104 residues long. MolForge cross-references it against 0 known binders and 55 disease associations.
- UniProt accession: Q5U5X0; gene symbol LYRM7.
- Organism: Homo sapiens.
- Length: 104 amino acids.
- Top disease associations (Open Targets): Isolated CoQ-cytochrome C reductase deficiency, mitochondrial disease and mitochondrial complex III deficiency nuclear type 1.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Complex III assembly factor LYRM7 |
|---|---|
| UniProt accession | Q5U5X0 |
| Gene | LYRM7 |
| Organism | Homo sapiens |
| Length | 104 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (55)
Diseases linked to this target (Open Targets).
- Isolated CoQ-cytochrome C reductase deficiency · score 0.76
- mitochondrial disease · score 0.37
- mitochondrial complex III deficiency nuclear type 1 · score 0.34
- body mass index · score 0.23
- C-reactive protein measurement · score 0.16
- genetic disorder · score 0.15
- mosquito bite reaction itch intensity measurement · score 0.11
- glomerular filtration rate · score 0.11
- mosquito bite reaction size measurement · score 0.10
- creatinine measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5U5X0-F1 | alphafold | PREDICTED | 91.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5U5X0.
Amino-acid sequence (104 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LYRM7?
The strongest Open Targets associations for LYRM7 are Isolated CoQ-cytochrome C reductase deficiency, mitochondrial disease, mitochondrial complex III deficiency nuclear type 1, body mass index and C-reactive protein measurement.
How long is the LYRM7 protein?
The Homo sapiens LYRM7 protein (UniProt Q5U5X0) is 104 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5U5X0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5U5X0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.