Uncharacterized protein C12orf60 (C12orf60)
Homo sapiens — UniProt Q5U649
Data last refreshed: (UniProt release unknown)
Key facts
Uncharacterized protein C12orf60 (C12orf60) is a protein from Homo sapiens identified by UniProt accession Q5U649, 245 residues long. MolForge cross-references it against 0 known binders and 70 disease associations.
- UniProt accession: Q5U649; gene symbol C12orf60.
- Organism: Homo sapiens.
- Length: 245 amino acids.
- Top disease associations (Open Targets): lean body mass, grip strength measurement and fat body mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Uncharacterized protein C12orf60 |
|---|---|
| UniProt accession | Q5U649 |
| Gene | C12orf60 |
| Organism | Homo sapiens |
| Length | 245 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (70)
Diseases linked to this target (Open Targets).
- lean body mass · score 0.25
- grip strength measurement · score 0.23
- fat body mass · score 0.23
- blood protein measurement · score 0.23
- heel bone mineral density · score 0.20
- osteoarthritis, hand · score 0.19
- base metabolic rate measurement · score 0.18
- neurodegenerative disease · score 0.16
- appendicular lean mass · score 0.15
- BMI-adjusted hip circumference · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5U649-F1 | alphafold | PREDICTED | 80.81 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5U649.
Amino-acid sequence (245 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C12orf60?
The strongest Open Targets associations for C12orf60 are lean body mass, grip strength measurement, fat body mass, blood protein measurement and heel bone mineral density.
How long is the C12orf60 protein?
The Homo sapiens C12orf60 protein (UniProt Q5U649) is 245 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5U649 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5U649 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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