Zinc finger protein 468 (ZNF468)
Homo sapiens — UniProt Q5VIY5
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 468 (ZNF468) is a protein from Homo sapiens identified by UniProt accession Q5VIY5, 522 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.
- UniProt accession: Q5VIY5; gene symbol ZNF468.
- Organism: Homo sapiens.
- Length: 522 amino acids.
- Top disease associations (Open Targets): serum urea measurement, cystatin C measurement and creatinine measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 468 |
|---|---|
| UniProt accession | Q5VIY5 |
| Gene | ZNF468 |
| Organism | Homo sapiens |
| Length | 522 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (23)
Diseases linked to this target (Open Targets).
- serum urea measurement · score 0.26
- cystatin C measurement · score 0.26
- creatinine measurement · score 0.26
- hematocrit · score 0.21
- breast cancer · score 0.07
- hemoglobin measurement · score 0.06
- esophageal squamous cell carcinoma · score 0.04
- mean corpuscular volume · score 0.04
- mean reticulocyte volume · score 0.03
- cancer · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5VIY5-F1 | alphafold | PREDICTED | 64.97 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VIY5.
Amino-acid sequence (522 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF468?
The strongest Open Targets associations for ZNF468 are serum urea measurement, cystatin C measurement, creatinine measurement, hematocrit and breast cancer.
How long is the ZNF468 protein?
The Homo sapiens ZNF468 protein (UniProt Q5VIY5) is 522 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5VIY5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5VIY5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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