Sperm protein associated with the nucleus on the X chromosome N1 (SPANXN1)
Homo sapiens — UniProt Q5VSR9
Data last refreshed: (UniProt release unknown)
Key facts
Sperm protein associated with the nucleus on the X chromosome N1 (SPANXN1) is a protein from Homo sapiens identified by UniProt accession Q5VSR9, 72 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.
- UniProt accession: Q5VSR9; gene symbol SPANXN1.
- Organism: Homo sapiens.
- Length: 72 amino acids.
- Top disease associations (Open Targets): pancreatic adenocarcinoma, cancer and schizophrenia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sperm protein associated with the nucleus on the X chromosome N1 |
|---|---|
| UniProt accession | Q5VSR9 |
| Gene | SPANXN1 |
| Organism | Homo sapiens |
| Length | 72 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (4)
Diseases linked to this target (Open Targets).
- pancreatic adenocarcinoma · score 0.04
- cancer · score 0.01
- schizophrenia · score 0.00
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5VSR9-F1 | alphafold | PREDICTED | 68.51 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VSR9.
Amino-acid sequence (72 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPANXN1?
The strongest Open Targets associations for SPANXN1 are pancreatic adenocarcinoma, cancer, schizophrenia and neoplasm.
How long is the SPANXN1 protein?
The Homo sapiens SPANXN1 protein (UniProt Q5VSR9) is 72 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5VSR9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5VSR9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.