Fibronectin type III domain-containing protein 7 (FNDC7)
Homo sapiens — UniProt Q5VTL7
Data last refreshed: (UniProt release unknown)
Key facts
Fibronectin type III domain-containing protein 7 (FNDC7) is a protein from Homo sapiens identified by UniProt accession Q5VTL7, 733 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.
- UniProt accession: Q5VTL7; gene symbol FNDC7.
- Organism: Homo sapiens.
- Length: 733 amino acids.
- Top disease associations (Open Targets): mean platelet volume, hypertriglyceridemia 2 and hypoalphalipoproteinemia, primary, 2, intermediate.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Fibronectin type III domain-containing protein 7 |
|---|---|
| UniProt accession | Q5VTL7 |
| Gene | FNDC7 |
| Organism | Homo sapiens |
| Length | 733 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (28)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.35
- hypertriglyceridemia 2 · score 0.06
- hypoalphalipoproteinemia, primary, 2, intermediate · score 0.06
- cholesterol-ester transfer protein deficiency · score 0.06
- plasma fibronectin deficiency · score 0.05
- Combined hyperlipidemia · score 0.05
- thyroid hormone metabolism, abnormal, 2 · score 0.05
- sitosterolemia · score 0.05
- homozygous familial hypercholesterolemia · score 0.05
- hypercholesterolemia, autosomal dominant, 3 · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5VTL7-F1 | alphafold | PREDICTED | 86.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VTL7.
Amino-acid sequence (733 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FNDC7?
The strongest Open Targets associations for FNDC7 are mean platelet volume, hypertriglyceridemia 2, hypoalphalipoproteinemia, primary, 2, intermediate, cholesterol-ester transfer protein deficiency and plasma fibronectin deficiency.
How long is the FNDC7 protein?
The Homo sapiens FNDC7 protein (UniProt Q5VTL7) is 733 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5VTL7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5VTL7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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