Nuclear pore membrane glycoprotein 210-like (NUP210L)

Homo sapiens — UniProt Q5VU65

Gene: NUP210LHomo sapiensSwissProt reviewed

Data last refreshed: 2026-04-18 (UniProt release unknown)

Key facts

Nuclear pore membrane glycoprotein 210-like (NUP210L) is a protein from Homo sapiens identified by UniProt accession Q5VU65, 1888 residues long. MolForge cross-references it against 0 known binders and 138 disease associations.

UniProt accession: Q5VU65; gene symbol NUP210L.
Organism: Homo sapiens.
Length: 1888 amino acids.
Top disease associations (Open Targets): mean platelet volume, platelet count and mathematical ability.
3D structure: AlphaFold model available.

Target properties

Protein name	Nuclear pore membrane glycoprotein 210-like
UniProt accession	Q5VU65
Gene	NUP210L
Organism	Homo sapiens
Length	1888 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (138)

Diseases linked to this target (Open Targets).

mean platelet volume · score 0.39
platelet count · score 0.39
mathematical ability · score 0.33
platelet component distribution width · score 0.32
neurodegenerative disease · score 0.30
serum gamma-glutamyl transferase measurement · score 0.28
triglyceride measurement · score 0.22
diet measurement · score 0.22
Immature Reticulocyte Fraction Measurement · score 0.21
mean reticulocyte volume · score 0.19

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5VU65-F1	alphafold	PREDICTED	79.49	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VU65.

Amino-acid sequence (1888 residues)

MTGCPASSRR RGFGLFFFLR LHRLLLLFLV LRGTLANKLN VPQVLLPFGR EPGRVPFLLE AQRGCYTWHS THHDAVTVEP LYENGTLCSQ KAVLIAESTQ PIRLSSIILA REIVTDHELR CDVKVDVINS IEIVSRAREL YVDDSPLELM VRALDAEGNT FSSLAGMMFE WSIAQDNESA REELSSKIRI LKYSEAEYAP PIYIAEMEKE EKQGDVILVS GIRTGAAVVK VRIHEPFYKK VAAALIRLLV LENIFLIPSH DIYLLVGTYI KYQVAKMVQG RVTEVKFPLE HYILELQDHR VALNGSHSEK VAILDDKTAM VTASQLGQTN LVFVHKNVHM RSVSGLPNCT IYVVEPGFLG FTVQPGNRWS LEVGQVYVIT VDVFDKSSTK VYISDNLRIT YDFPKEYFEE QLTTVNGSYH IVKALKDGVV VINASLTSII YQNKDIQPIK FLIKHQQEVK IYFPIMLTPK FLAFPHHPMG MLYRYKVQVE GGSGNFTWTS SNETVVIVTT KGVVTAGQVR GNSTVLARDV QNPFRYGEIK IHVLKLNKME LLPFHADVEI GQIIEIPIAM YHINKETKEA MAFTDCSHLS LDLNMDKQGV FTLLKEGIQR PGPMHCSSTH IAAKSLGHTL VTVSVNECDK YLESSATFAA YEPLKALNPV EVALVTWQSV KEMVFEGGPR PWILEPSRFF LELNAEKTEK IGIAQVWLPS KRKQNQYIYR IQCLDLGEQV LTFRIGNHPG VLNPSPAVEV LQVRFICAHP ASMSVTPVYK VPAGAQPCPL PQHNKWLIPV SRLRDTVLEL AVFDQHRRKF DNFSSLMLEW KSSNETLAHF EDYKSVEMVA KDDGSGQTRL HGHQILKVHQ IKGTVLIGVN FVGYSEKKSP KEISNLPRSV DVELLLVDDV TVVPENATIY NHPDVKETFS LVEGSGYFLV NSSEQGVVTI TYMEAESSVE LVPLHPGFFT LEVYDLCLAF LGPATAHLRV SDIQELELDL IDKVEIDKTV LVTVRVLGSS KRPFQNKYFR NMELKLQLAS AIVTLTPMEQ QDEYSENYIL RATTIGQTTL VAIAKDKMGR KYTSTPRHIE VFPPFRLLPE KMTLIPMNMM QVMSEGGPQP QSIVHFSISN QTVAVVNRRG QVTGKIVGTA VVHGTIQTVN EDTGKVIVFS QDEVQIEVVQ LRAVRILAAA TRLITATKMP VYVMGVTSTQ TPFSFSNANP GLTFHWSMSK RDVLDLVPRH SEVFLQLPVE HNFAMVVHTK AAGRTSIKVT VHCMNSSSGQ FEGNLLELSD EVQILVFEKL QLFYPECQPE QILMPINSQL KLHTNREGAA FVSSRVLKCF PNSSVIEEDG EGLLKAGSIA GTAVLEVTSI EPFGVNQTTI TGVQVAPVTY LRVSSQPKLY TAQGRTLSAF PLGMSLTFTV QFYNSIGEKF HTHNTQLYLA LNRDDLLHIG PGNKNYTYMA QAVNRGLTLV GLWDRRHPGM ADYIPVAVEH AIEPDTKLTF VGDIICFSTH LVSQHGEPGI WMISANNILQ TDIVTGVGVA RSPGTAMIFH DIPGVVKTYR EVVVNASSRL MLSYDLKTYL TNTLNSTVFK LFITTGRNGV NLKGFCTPNQ ALAITKVLLP ATLMLCHVQF SNTLLDIPAS KVFQVHSDFS MEKGVYVCII KVRPQSEELL QALSVADTSV YGWATLVSER SKNGMQRILI PFIPAFYINQ SELVLSHKQD IGEIRVLGVD RVLRKLEVIS SSPVLVVAGH SHSPLTPGLA IYSVRVVNFT SFQQMASPVF INISCVLTSQ SEAVVVRAMK DKLGADHCED SAILKRFTGS YQILLLTLFA VLASTASIFL AYNAFLNKIQ TVPVVYVPTL GTPQPGFFNS TSSPPHFMSL QPPLAQSRLQ HWLWSIRH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with NUP210L?

The strongest Open Targets associations for NUP210L are mean platelet volume, platelet count, mathematical ability, platelet component distribution width and neurodegenerative disease.

How long is the NUP210L protein?

The Homo sapiens NUP210L protein (UniProt Q5VU65) is 1888 amino acids long.

Browse: Targets: N · all protein targets A–Z · drugs A–Z.

Sources

UniProtKB Q5VU65 — name, gene, function, sequence, keywords (CC BY 4.0)
AlphaFold DB Q5VU65 — predicted 3D structure (CC BY 4.0)
Open Targets Platform — disease associations and tractability (CC0)

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.