Cilia- and flagella-associated protein 141 (CFAP141)
Homo sapiens — UniProt Q5VU69
Data last refreshed: (UniProt release unknown)
Key facts
Cilia- and flagella-associated protein 141 (CFAP141) is a protein from Homo sapiens identified by UniProt accession Q5VU69, 101 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.
- UniProt accession: Q5VU69; gene symbol CFAP141.
- Organism: Homo sapiens.
- Length: 101 amino acids.
- Top disease associations (Open Targets): Immature Reticulocyte Fraction Measurement, platelet count and mean corpuscular hemoglobin.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cilia- and flagella-associated protein 141 |
|---|---|
| UniProt accession | Q5VU69 |
| Gene | CFAP141 |
| Organism | Homo sapiens |
| Length | 101 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- Immature Reticulocyte Fraction Measurement · score 0.06
- platelet count · score 0.05
- mean corpuscular hemoglobin · score 0.05
- diet measurement · score 0.04
- protein measurement · score 0.04
- mean platelet volume · score 0.03
- reticulocyte measurement · score 0.02
- blood protein measurement · score 0.02
- mean corpuscular hemoglobin concentration · score 0.02
- mean corpuscular volume · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5VU69-F1 | alphafold | PREDICTED | 93.78 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5VU69.
Amino-acid sequence (101 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CFAP141?
The strongest Open Targets associations for CFAP141 are Immature Reticulocyte Fraction Measurement, platelet count, mean corpuscular hemoglobin, diet measurement and protein measurement.
How long is the CFAP141 protein?
The Homo sapiens CFAP141 protein (UniProt Q5VU69) is 101 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5VU69 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5VU69 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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